43577-Ephrem, Georges

Georges Ephrem, MD

Assistant Professor of Clinical Medicine

Methodist KIC E371
Indianapolis, IN


Dr. Georges Ephrem is a clinical and interventional adult congenital, coronary and structural heart diseases specialist at Indiana University Health Physicians, and an Assistant Professor of Clinical Medicine at the Indiana University School of Medicine. He completed his internal medicine residency and cardiovascular diseases fellowship in New York along with a chief resident year and a Masters of Science in Clinical Research Methods. His clinical adult congenital heart disease training was at Emory University in Atlanta, GA. He completed his interventional training at William Beaumont in Michigan and his structural and congenital interventional fellowship at the University of Toronto. He is a Fellow of the American College of Physicians, the American College of Cardiology and the Society for Cardiovascular Angiography and Interventions. He is board certified in medicine, cardiovascular diseases, interventional cardiology, echocardiography, nuclear cardiology, and adult congenital heart disease. He received awards and peer recognition for his research. His main investigative interest is outcomes research in the adult congenital heart disease population, especially in the transition of proven therapies in the general patient population to the adult congenital population. He has published a series of articles, including many in the highest impact journals such as JACC and JACC: Cardiovascular Interventions, pertaining to this field as well as to innovative approaches in catheterization of cardiac patients in general, and the adult congenital population in particular.

Key Publications

A Quain, M Hoyer, G Ephrem, WA Kay. Non-invasive cardiac output monitoring (NICOM) in adult congenital heart disease patients with Fontan palliation. International Journal of Cardiology Congenital Heart Disease, 100287.

MH Bahrami, HZ Ansari, M Guglin, G Ephrem, GE Revtyak. Isolated congenital cleft mitral valve leaflet: a rare cause of refractory cardiogenic shock complicating acute myocardial infarction. Journal of Congenital Cardiology 5 (1), 1-5

Broberg CS, Kovacs AH, Sadeghi S, Rosenbaum MS, Lewis MJ, Carazo MR, Rodriguez FH 3rd, Halpern DG, Feinberg J, Galilea FA, Baraona F, Cedars AM, Ko JM, Porayette P, Maldonado J, Sarubbi B, Fusco F, Frogoudaki AA, Nir A, Chaudhry A, John AS, Karbassi A, Hoskoppal AK, Frischhertz BP, Hendrickson B, Bouma BJ, Rodriguez-Monserrate CP, Broda CR, Tobler D, Gregg D, Martinez-Quintana E, Yeung E, Krieger EV, Ruperti-Repilado FJ, Giannakoulas G, Lui GK, Ephrem G, Singh HS, Almeneisi HM, Bartlett HL, Lindsay I, Grewal J, Nicolarsen J, Araujo JJ, Cramer JW, Bouchardy J, Al Najashi K, Ryan K, Alshawabkeh L, Andrade L, Ladouceur M, Schwerzmann M, Greutmann M, Meras P, Ferrero P, Dehghani P, Tung PP, Garcia-Orta R, Tompkins RO, Gendi SM, Cohen S, Klewer S, Hascoet S, Mohammadzadeh S, Upadhyay S, Fisher SD, Cook S, Cotts TB, Aboulhosn JA. COVID-19 in Adults With Congenital Heart Disease. J Am Coll Cardiol. 2021 Apr 6;77(13):1644-1655.

Bou Chaaya RG, Herrmann JL, Rao RA, Fisch MD, Ephrem G. Case Report: Constrictive Pericarditis in a Patient With Isolated Anomalous Right Upper Pulmonary Venous Return. Front Cardiovasc Med. 2020 Dec 9;7:612014.

Ezzeddine FM, Moe T, Ephrem G, Kay WA. Do we have the ACHD physician resources we need to care for the burgeoning ACHD population? Congenit Heart Dis. 2019 Jul;14(4):511-516.

Ephrem G, Hebson C, John A, Moore E, Jokhadar M, Ford R, Veldtman G, Dori Y, Gurvitz M, Kogon B, Kovacs A, Roswick M, McConnell M, Book WM, Rodriguez F 3rd. Frontiers in Fontan failure: Innovation and improving outcomes: A conference summary. Congenit Heart Dis. 2019 Mar;14(2):128-137.

Titles & Appointments

  • Assistant Professor of Clinical Medicine

Looking for patient care?

To schedule an appointment with a faculty member physician of IU School of Medicine, contact Indiana University Health at 888-484-3258 or use the physician finder by clicking the button below.

Find a doctor