Mohamed S. El Masry, MSC, PhD, MD

Bio

Dr. El Masry currently serves as an assistant professor, Division of Plastic Surgery, Department of Surgery at Indiana University and as an investigator at the Indiana Center for Regenerative Medicine and Engineering. Dr. El Masry received his medical degree from School of Medicine, Zagazig University, where he also completed his general surgery residency and plastic surgery training. He obtained his doctoral degree in Plastic Surgery from School of Medicine/Zagazig University & The Ohio State University via a conjoint governmental sponsored mission. Prior to joining Indiana University, Dr. El Masry joined The Ohio State University, Department of Surgery as a research scholar from 2016-2018. He previously served as an assistant lecturer at department of Plastic Surgery, Zagazig University from 2012-2018. Dr. El Masry has published in peer-reviewed journals such as Molecular Therapy and The Federation of American Societies for Experimental Biology (FASEB J).

Key Publications

El Masry, M. S., Chaffee, S., Das Ghatak, P., Mathew-Steiner, S. S., Das, A., Higuita-Castro, N., Roy, S., Anani, R. A., & Sen, C. K. (2019). Stabilized collagen matrix dressing improves wound macrophage function and epithelialization. FASEB J, 33(2), 2144-2155.

Ahmed, N. S., Ghatak, S., El Masry, M. S., Gnyawali, S. C., Roy, S., Amer, M., Everts, H., Sen, C. K., & Khanna, S. (2017). Epidermal E-Cadherin Dependent beta-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling. Mol Ther, 25(11), 2502-2512. (*Co 1st author).

Das, A., El Masry, M. S., Gnyawali, S. C., Ghatak, S., Singh, K., Stewart, R., Lewis, M., Saha, A., Gordillo, G., & Khanna, S. (2019). Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms. J Am Coll Nutr, 38(6), 526-536. (*Co 1st author).

Li, J., Ghatak, S., El Masry, M. S., Das, A., Liu, Y., Roy, S., Lee, R. J., & Sen, C. K. (2018). Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound. Mol Ther, 26(9), 2178-2188.

Sinha, M., Ghosh, N., Wijesinghe, D. S., Mathew-Steiner, S. S., Das, A., Singh, K., El Masry, M. S., Khanna, S., Inoue, H., Yamazaki, K., Kawada, M., Gordillo, G. M., Roy, S., & Sen, C. K. (2021). Pseudomonas Aeruginosa Theft Biofilm Require Host

Titles & Appointments

Assistant Research Professor of Surgery

Education

2019 PhD Zagazig University

2012 MSC Zagazig University

2007 MD Zagazig University
Research

Dr. El Masry is a plastic surgeon scientist serving as a co-I on many grants funded by NIH and the Department of Defense. His research focus is regenerative medicine in wound healing.

Critical limb Ischemia (CLI) carries about 25% to 40% risk of major amputation with 20% annual mortality; Therefore, it is critical to develop novel therapeutics that can rescue the tissues and decrease the amputation rate. The limitation to clinical translation is the lack of a large animal model that mimic the ischemic myopathy changes seen in PAD or CLI. Dr. El Masry developed a clinically relevant swine model that recapitulates features characteristic of human CLI reproducibly that is validated comprehensively by both non-invasive and invasive assessment and lends itself to detailed mechanistic studies and interventional drug testing.

Wound Care Dressings. Dr. El Masry studied the effect of tissue scaffolds on the wound microenvironment by utilizing stabilized collagen matrix dressing. The results of this study showed that the dressing contributed to the rapidly resolution of the inflammation at the wound site; additionally, the scaffold bolstered the expression of antimicrobial peptides that decreased the biofilm formation, rapid reepithelization, improved collagen deposition and maturation with overall better wound healing outcome. Dr. El Masry is currently working on a novel wound care dressing to combat multidrug resistant biofilm.

Google Scholar
Professional Organizations

American Society of Plastic Surgeons

Egyptian Society of Plastic and Reconstructive Surgeons (ESPRS)

Egyptian Society of Surgeons (ESS)

Wound Healing Society

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