Scott G. Canfield, PhD
Associate Professor of Anatomy, Cell Biology & Physiology
Charles O. Sankey Jr Scholar in Pathology
Adjunct Associate Professor of Pathology & Laboratory Medicine
- Address
-
620 Chestnut St.
HH 135
Terre Haute, IN 47809 - PubMed:
-
Key Publications
Gopinadhan A, Hughes JM, Conroy AL, John CC, Canfield SG, Datta D. (Co-Corresponding Author). A Human Pluripotent Stem Cell-Derived In Vitro Model of the Blood-Brain Barrier in Cerebral Malaria. Fluids and Barriers. Fluids Barriers CNS. 2024 May 1;21(1):38. doi: 10.1186/s12987-024-00541-9.
Hughes JM, Neese OR, Bieber DD, Lewis KA, Ahmadi LM, Parsons DW, Canfield SG. The Effects of Propofol on a Human In Vitro Blood-Brain Barrier Model. Front Cell Neurosci. 2022 May 11;16:835649.
Canfield SG, Stebbins MJ, Faubion MG, Palecek SP, Shusta EV. An Isogenic Neurovascular Unit Model Comprised of Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells, Pericytes, Astrocytes, and Neurons. Fluids and Barriers. 2019 Aug7;16(1).
Canfield SG, Stebbins MJ, Morales BS, Asai SW, Vatine GD, Svendsen CN, Palecek SP, Shusta EV. An Isogenic Blood-Brain Barrier Comprising Brain Endothelial Cells, Astrocytes and Neurons Derived from Human Induced Pluripotent Stem Cells. J Neurochem 2017 Mar;140(6):874-888.
| Year | Degree | Institution |
|---|---|---|
| 2013 | PhD | Medical College of Wisconsin |
| 2006 | BS | Northland College |
Dr. Canfield’s research program is centered on the development of a human stem cell-derived blood-brain barrier model consisting of brain microvascular endothelial cells, astrocytes, neurons, and pericytes. The stem cell-derived brain microvascular endothelial cells are responsive to inductive neuronal cues, expresses functional and active efflux transporters, tight junction proteins and nutrient transporters all contributing to a physiological barrier. His laboratory investigates how varying pathological conditions and environmental toxins can negatively affect the blood-brain barrier in an attempt to unveil novel therapeutic strategies.
Desc: Class of 2027 Professor of the Year
Scope: School
Date: 2024-04-01
Desc: Class of 2026 Professor of the Year
Scope: School
Date: 2023-04-01
Desc: 2022 Shellhammer Outstanding Teacher Award
Scope: School
Date: 2022-05-01
Desc: Class of 2022 Outstanding Teaching of Basic Science
Scope: School
Date: 2022-05-01
Desc: Trustees Teaching Award
Scope: University
Date: 2021-03-01
Desc: Class of 2022 Professor of the Year
Scope: School
Date: 2019-04-01