Stephen J. Jordan, MD, PhD

Faculty

Stephen J. Jordan, MD, PhD

Assistant Professor of Medicine

Phone (317) 274-8115

Address

MS 224E
INFD
IN
Indianapolis, IN

Bio

Dr. Jordan completed his internal medicine residency and infectious diseases fellowship at University of Alabama. His basic laboratory research involves investigation of the immunopathogenesis of sexually transmitted diseases in women, He currently provides inpatient and outpatient service at Eskenazi Hospital.

Titles & Appointments

Assistant Professor of Medicine
Assistant Professor of Microbiology & Immunology
ID Lab Assistant Director

Education

2011 MD University of Alabama at Birmingham

2009 PhD University of Alabama at Birmingham

2003 BSC Oklahoma City University
Publications

Sexual behavior shapes male genitourinary microbiome composition.
Toh E; Xing Y; Gao X; Jordan SJ; Batteiger TA; Batteiger BE; Van Der Pol B; Muzny CA; Gebregziabher N; Williams JA; Fortenberry LJ; Fortenberry JD; Dong Q; Nelson DE; Cell reports. Medicine 2023 Mar 21

Evaluation of Clinical, Gram Stain, and Microbiological Cure Outcomes in Men Receiving Azithromycin for Acute Nongonococcal Urethritis: Discordant Cures Are Associated With Mycoplasma genitalium Infection.
Toh E; Gao X; Williams JA; Batteiger TA; Coss LA; LaPradd M; Ren J; Geisler WM; Xing Y; Dong Q; Nelson DE; Jordan SJ; Sexually transmitted diseases 2022 Jan 1

No Pathogen-Specific Sign or Symptom Predicts the Etiology of Monomicrobial Nongonococcal Urethritis in Men.
Jordan SJ; Toh E; Williams JA; Fortenberry LJ; LaPradd M; Ryan JD; Nelson DE; Batteiger TA; Sexually transmitted diseases 2020 May

Case Report: Candida dubliniensis as a Cause of Chronic Meningitis.
Tahir M; Peseski AM; Jordan SJ; Frontiers in neurology 2020 Dec 8

Aetiology and prevalence of mixed-infections and mono-infections in non-gonococcal urethritis in men: a case-control study.
Jordan SJ; Toh E; Williams JA; Fortenberry L; LaPradd ML; Katz BP; Batteiger BE; Nelson DE; Batteiger TA; Sexually transmitted infections 2019 Sep 12

Reply to, "Proceed With Caution in Generating Evidence in the 'Oropharyngeal-Anorectal Chlamydia Hypothesis' in Humans".
Batteiger TA; Jordan SJ; Toh E; Nelson DE; Sexually transmitted diseases 2019 Sep

Delay in Seeking Health Care Services After Onset of Urethritis Symptoms in Men.
Aaron KJ; Van Der Pol B; Jordan SJ; Schwebke JR; Hook EW 3rd; Sexually transmitted diseases 2019 May

Detection of Rectal Chlamydia trachomatis in Heterosexual Men Who Report Cunnilingus.
Batteiger TA; Jordan SJ; Toh E; Fortenberry L; Williams JA; LaPradd M; Katz B; Fortenberry JD; Dodge B; Arno J; Batteiger BE; Nelson DE; Sexually transmitted diseases 2019 Jul

An Adaptive Chlamydia trachomatis-Specific IFN-?-Producing CD4+ T Cell Response Is Associated With Protection Against Chlamydia Reinfection in Women.
Bakshi RK; Gupta K; Jordan SJ; Chi X; Lensing SY; Press CG; Geisler WM; Frontiers in immunology 2018 Sep 7

Stimulated peripheral blood mononuclear cells from chlamydia-infected women release predominantly Th1-polarizing cytokines.
Jordan SJ; Bakshi RK; Brown LT; Chi X; Geisler WM; Cytokine 2018 Jun 18

Defining the Urethritis Syndrome in Men Using Patient Reported Symptoms
Jordan SJ, Aaron KJ, Schwebke JR, Van Der Pol BJ, Hook EW 3rd Sexually transmitted diseases 2018 Jan 16

Meatal Swabs Contain Less Cellular Material and Are Associated with a Decrease in Gram Stain Smear Quality Compared to Urethral Swabs in Men.
Jordan SJ; Schwebke JR; Aaron KJ; Van Der Pol B; Hook EW 3rd; Journal of clinical microbiology 2017 May 10

Lower Levels of Cervicovaginal Tryptophan Are Associated With Natural Clearance of Chlamydia in Women.
Jordan SJ; Olson KM; Barnes S; Wilson LS; Berryhill TF; Bakshi R; Brown LT; Press CG; Geisler WM; The Journal of infectious diseases 2017 Jun 15

Immunoglobulin-Based Investigation of Spontaneous Resolution of Chlamydia trachomatis Infection.
Bakshi RK; Gupta K; Jordan SJ; Brown LT; Press CG; Gorwitz RJ; Papp JR; Morrison SG; Lee JY; Morrison RP; Geisler WM; The Journal of infectious diseases 2017 Jun 1

Utilization of the Cepheid Xpert® CT/NG Sample Adequacy Control to Determine the Influence of the Urethral Swab on Cellular Content in Post-Swab versus Pre-Swab Urine.
Jordan SJ; Van Der Pol B; Hook EW Iii Md; Sexually transmitted diseases 2017 Jan

T cell phenotypes in women with Chlamydia trachomatis infection and influence of treatment on phenotype distributions.
Ogendi BMO; Bakshi RK; Gupta K; Kapil R; Brown LT; Jordan SJ; Sabbaj S; Press CG; Lee JY; Geisler WM; Microbes and infection 2017 Dec 26

The Predominant CD4+ Th1 Cytokine Elicited to Chlamydia trachomatis Infection in Women Is Tumor Necrosis Factor Alpha and Not Interferon Gamma.
Jordan SJ; Gupta K; Ogendi BM; Bakshi RK; Kapil R; Press CG; Sabbaj S; Lee JY; Geisler WM; Clinical and vaccine immunology : CVI 2017 Apr 5

Acute Cryptococcal Immune Reconstitution Inflammatory Syndrome in a Patient on Natalizumab.
Gundacker ND; Jordan SJ; Jones BA; Drwiega JC; Pappas PG; Open forum infectious diseases 2016 Feb 17

Azithromycin for rectal chlamydia: is it time to leave azithromycin on the shelf?...Not yet.
Jordan SJ; Geisler WM; Sexually transmitted diseases 2014 Feb

Malaria immunoepidemiology in low transmission: correlation of infecting genotype and immune response to domains of Plasmodium falciparum merozoite surface protein 3.
Jordan SJ; Oliveira AL; Hernandez JN; Oster RA; Chattopadhyay D; Branch OH; Rayner JC; Infection and immunity 2011 Mar 7

Antibodies directed against merozoite surface protein-6 are induced by natural exposure to Plasmodium falciparum in a low transmission environment.
Jordan SJ; Oliveira AL; Neal AT; Hernandez JN; Branch OH; Rayner JC; Parasite immunology 2011 Jul

Limited variation in vaccine candidate Plasmodium falciparum Merozoite Surface Protein-6 over multiple transmission seasons.
Neal AT; Jordan SJ; Oliveira AL; Hernandez JN; Branch OH; Rayner JC; Malaria journal 2010 May 24

Genetic diversity of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-3 in a hypoendemic transmission environment.
Jordan SJ; Branch OH; Castro JC; Oster RA; Rayner JC; The American journal of tropical medicine and hygiene 2009 Mar

Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility.
Byrum J; Jordan S; Safrany ST; Rodgers W; Nucleic acids research 2004 May 18

T cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses.
Jordan S; Rodgers W; Journal of immunology (Baltimore, Md. : 1950) 2003 Jul 1

Transient association of Ku with nuclear substrates characterized using fluorescence photobleaching.
Rodgers W; Jordan SJ; Capra JD; Journal of immunology (Baltimore, Md. : 1950) 2002 Mar 1
Professional Organizations

American Physician Scientist Association

American Sexually Transmitted Diseases Association

Infectious Diseases Society of America
Board Certifications

American Board of Internal Medicine - Internal Medicine
Clinical Interests

My basic laboratory research involves investigation of the immunopathogenesis of sexually transmitted diseases in women. I am currently focused on exploring the immune response(s) in women infected with Chlamydia trachomatis, a major cause of pelvic disease in women that can lead to infertility, chronic pelvic pain, and an increased risk for ectopic pregnancy and HIV acquisition. In order to better understand the immune response to chlamydial infection in humans, I am using stored specimens from a large ongoing cohort study of uncomplicated chlamydia infection in women to identify novel immune correlates of protection, which will advance chlamydia vaccine development and lay the foundation for future cohort studies to further explore the mechanisms of effective immune responses to chlamydia.

Research Labs

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Faculty Labs