21706-O'Neil, Kathleen

Kathleen M. O'Neil, MD

Professor Emeritus of Clinical Pediatrics

Phone
(317) 274-2172
Address
RR 307
PRHU
IN
Indianapolis, IN
PubMed:

Bio

Dr. O'Neil is a Professor of Pediatrics at Indiana University School of Medicine in the Division of Pediatric Rheumatology. She studied at Tufts University School of Medicine in Boston, the Yale-New Haven Hospital in New Haven, CT and the Johns Hopkins School of Medicine in Baltimore. She has taught at the University of Maryland, SUNY at Buffalo, and University of Oklahoma before moving to IU in 2012. Clinical interests include all pediatric rheumatic conditions, especially severe multisystem disorders (SLE, juvenile dermatomyositis, vasculitis, sclerodermas and autoinflammatory diseases). She participates in multi-center research including the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Childhood Arthritis and Rheumatology Research Alliance (CARRA). She was a founding member of CARRA. She coordinates a multi-center study of hormone effects during puberty on disease activity and autoimmunity in childhood SLE. Her work strives to understand why autoimmune diseases are more frequent in girls, and why many begin or worsen near puberty. She participates in multi-center trials of novel medications in childhood rheumatic diseases and is a leader in national and international research organizations.

Key Publications

1.     Brunner HI, Bennett MR, Abulaban K, Klein-Gitelman MS, O’Neil KM, Tucker L, Ardoin SP, Rouster-Stevens KA, Onel KB, Singer NG, Eberhard AB, Jung JK, Imundo L, Wright TB, Witte D, Rovin BH, Ying J, Devarajan P.  Development of a novel renal activity index of lupus nephritis in children and young adults.  Arthritis Care & Research 68:1003-1011.  2016.  UI: 26473509

2.     Westwell-Roper C, Lubieniecka JM, Brown KL, Morishita KA, Mammen C, Wagner-Weiner L, Yen E, Li SC, O'Neil KM, Lapidus SK, Brogan P, Cimaz R, Cabral DA; for ARChiVe Investigators Network within the PedVas initiative. Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international clinician survey.  Pediatr Rheumatol Online J. 2017. 15:61. doi: 10.1186/s12969-017-0191-z.

3.     Bernatsky S, Clarke AE, Niaki OZ, Labrecque J, Schanberg LE, Silverman ED, Hayward K, Imundo L, Brunner HI, Haines KA, Cron RQ, Oen K, Wagner-Weiner L, Rosenberg AM, O'Neil KM, Duffy CM, von Scheven E, Joseph L, Lee JL, Ramsey-Goldman R.  J Rheumatol. 2017. pii: jrheum.170179. doi: 10.3899/jrheum.170179. PMID:  28765255

4.     Go EJL, O'Neil KM.  Curr Opin Rheumatol. The catastrophic antiphospholipid syndrome in children.2017 Sep;29(5):516-522. doi: 10.1097/BOR.0000000000000426.  PMID:  28632503.

 

5.     Moncrieffe H, Bennett MF, Tsoras M, Luyrink LK, Johnson AL, Xu H, Dare J, Becker ML, Prahalad S, Rosenkranz M, O'Neil KM, Nigrovic PA, Griffin TA, Lovell DJ, Grom AA, Medvedovic M, Thompson SD.  Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate.  Rheumatology (Oxford). 2017 1;56:1542-1551. doi: 10.1093/rheumatology/kex206.  PMID:  28582527

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