19496-Idrees, Muhammad

Muhammad T. Idrees, MD

Louis Y. Mazzini Professor of Pathology

IU Health Pathology Laboratory
350 W 11th Street, Room 6014

Indianapolis, IN 46202
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Dr. Idrees earned his medical degree from the University of Punjab and completed an Anatomic and Clinical Pathology residency at Mount Sinai School of Medicine in New York. Subsequently, he performed fellowships in gynecologic pathology, cytopathology, and surgical/genitourinary pathology. After finishing his training, he joined the faculty at Mount Sinai School of Medicine. In 2008, Dr. Idrees relocated to Indiana to pursue his career in genitourinary pathology at the Indiana University School of Medicine. Dr. Idrees is active in academics at state, national and international levels. He has presented at national and international meetings and has published more than 150 peer-reviewed articles in renowned journals. He has served as an expert for WHO panels for 2016 and 2022 genitourinary tumor classification and has contributed several chapters to the WHO classification and several other pathology books. Dr. Idrees has served on multiple committees at the University level, including medical school student selection and executive selection committees. Currently, he is a tenured and titled professor of Pathology and Laboratory Medicine. He has served as the director of pathology laboratories and vice chair of clinical pathology at the IU academic health center between 2020-2023. He additionally has the charge of directing the Immunohistochemistry clinical and research laboratories. He is the director of genitourinary pathology fellowship program, the only ACGME accredit program in nation.  Dr. Idrees loves teaching and is the director of physician observer programs and recruit many of the pathology residents through this international outreach platform. Dr. Idrees is currently pursuing Executive physician MBA program at Kelley School of Business. Dr. Idrees resides in Carmel and is a great proponent of keeping a healthy life and work balance. He likes to travel, read, hike, play cricket and spend time with his wife and four children.

Key Publications


  • Katrina Collins, Andres M. Acosta, Stephanie E. Siegmund, Muhammad Idrees. Genetic profiling uncovers genome-wide loss of heterozygosity and provides insight in carcinogenesis of sarcomatoid transformation of chromophobe renal cell carcinoma. Mod Pathol. 2023. PMID: 38043790
  • Acosta AM, Idrees MT, Collins K, Masterson T, Ulbright TM. Primary Mullerian-type clear cell carcinoma of the seminal vesicle presenting as a testicular mass. Histopathology. 2023. PMID: 38043790  
  • Al-Obaidy KI, Magers MJ, Idrees MT. Testicular Cancer: Contemporary Updates in Staging. Surg Pathol Clin. 2022. PMID: 36344187
  • Collins K, Sholl LM, Vargas SO, Cornejo KM, Kravtsov O, Dickson BC, Idrees MT, Ulbright TM, Acosta AM. Testicular Juvenile Granulosa Cell Tumors Demonstrate Recurrent Loss of Chromosome 10 and Absence of Molecular Alterations Described in Ovarian Counterparts. Mod Pathol. 2023. PMID: 36813116
  • Gondim DD, Al-Obaidy KI, Idrees MT, Eble JN, Cheng L. Artificial intelligence-based multi-class histopathologic classification of kidney neoplasms. PMID: 36915914
  • Yu S, Sholl LM, Siegmund S, Ulbright TM, Collins K, Colecchia M, Del Pilar Gonzalez-Peramato M, Michalová K, Gordetsky JB, Cornejo KM, Kao CS, Wobker SE, Vargas SO, Maclean F, Idrees MT, Anderson WJ, Fletcher CDM, Acosta AM. Large cell calcifying Sertoli cell tumour: molecular and immunohistochemical assessment of a series comprising non-metastasising and metastasising neoplasms. Histopathology 2023. PMID: 36929593.
  • Nova-Camacho LM, Acosta AM, Trpkov K, Sangoi AR, Pierre A, Chou A, Yilmaz A, Morini A, Rodrigues Â, Fletcher CDM, Perez-Montiel D, Maclean F, Contreras F, Queipo FJ, Muñiz Unamunzaga G, Mesa H, de Torres I, Ruiz I, Alvarado-Cabrero I, Lobo J, Schwartz L, Cheng L, Akgul M, García-Martos M, Palmer MB, Aron M, Raspollini MR, Manrique Celada M, Hwang M, Idrees MT, Rioux-Leclercq N, Zalles N, Vergara N, Lal P, Wobker S, Kammerer-Jacquet SF, Prendeville S, Tilmant T, Ulbright TM, Verkarre V, Collins K, Williamson SR, Panizo A. Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration. Human Pathology 2023. PMID: 37331529
  • Siegmund SE, Al-Obaidy KI, Tsai HK, Idrees MT, Akgul M, Acosta AM, Hirsch MS. Concordance of MTOR Pathway Mutations and the Diagnosis of Renal Low-Grade Oncocytic Tumor (LOT). Hum Pathol. 2023. PMID: 37357748
  • Clinicopathologic and molecular spectrum of testicular sex cord-stromal tumors not amenable to specific histopathologic subclassification. Mod Pathol. 2022 PMID: 36180576
  • Molecular analysis of adenocarcinomas of the rete testis demonstrates frequent alterations in genes involved in cell cycle regulation. Histopathology. 2022 PMID: 35395117


  1. Genitourinary Diagnostic Pathology. Third Edition, Elsevier, 2022 Editors Amin, Tickoo Authors: Paner, Smith, Shen, Valezquez, Idrees, Al-Ahmadie, Cubilla, Ro, Reuter
  1. Tumors and tumor-like lesions of the testis and adjacent structures. American Registry of Pathology (ARP), 2022. Authors: Thomas Ulbright, Chia-Sui Kao, Sean Williamson, Muhammad T Idrees

Titles & Appointments

  • Louis Y. Mazzini Professor of Pathology
  • Director Genitourinary Pathology Fellowship
  • Director Immunohistochemistry Research Laboratory
  • Director Pathology Global Outreach Program
  • Director Immunohistochemistry Laboratories
  • Staff Pathologist and Tenured Pathologist Indiana University Health (formerly Clarian Health Partners and includes IU Health University Hospital, Riley Hospital for Children at IU Health, IU Health Methodist Hospital, IU Health West Hospital, IU Health No
  • Staff Pathologist and Tenured Pathologist Roudebush Veteran Administration Medical Center, Indianapolis, IN (Consultant Pathologist)
  • Education
    2024 MBA Kelley School of Business, Indiana University, Indiana
    2007 FEL Fellowship in Cytopathology , Mount Sinai School of Medicine, NY
    2006 FEL Fellowship Gynecological Pathology, Mount Sinai School of Medicine, NY
    2004 RES Pathology Residency, Mount Sinai School of Medicine, NY
    1995 MB,BS University of the Punjab
    1988 NA Government Degree College
  • Research

    Surgical pathology, Cytopathology, Urologic pathology

  • Professional Organizations
    American Society of Cytopathology
    Association of Physicians of Pakistani Descent of North America
    Cytopathology Society of Indiana
    Indiana Association of pathologists
    International Society of Urologic Pathology
    Paleopathology Club
    United States and Canadian Academy of Pathology Fellow of College of American Pathologists

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