13608-Bidwell, Joseph
Faculty

Joseph P. Bidwell, PhD

Professor of Anatomy, Cell Biology, & Physiology

Bio

 

After earning a PhD from Case Western Reserve University, Joseph Bidwell did postdoctoral training at the Marine Biological Lab (WHOI Biology), the Mayo Clinic (Cell Biol) and at the University Massachusettes Medical Center (Molecular Biology).

Academic Appointments
1999-2009: IUSM Dept of Anatomy & Cell Biology Associate Professor
1999-2006: IUSD Dept of Periodontics Associate Professor

Honors
Shellhammer Teaching Award Department of Anatomy & Cell Biology IUSM 2010
Visiting Professor; Chulalongkorn and Naresuan Universities Thailand,1999 & 2004
Prestigious External Award Recognition (PEAR) IUSM 2003
R.R. Bensley Award, American Association of Anatomists 2002
The Distinguished Faculty Award for Research, IUSD 1999
Visiting Professor: Meikai University, Sakado, Japan 1997

Titles & Appointments

  • Professor of Anatomy, Cell Biology, & Physiology
  • Professor of Medical & Molecular Genetics
  • Education
    1993 FEL University of Massachusetts Medical Center
    1990 FEL Mayo Clinic
    1988 FEL Marine Biological Lab/WHOI Biology
    1983 PhD Case Western Reserve University
    1975 BS Bowling Green State University
  • Research

    The Bidwell laboratory has an active program in elucidating the cellular and molecular mechanisms that underlie the skeleton’s response to anabolic stimuli, including parathyroid hormone (PTH), a potent osteoanabolic used to treat osteoporosis.  A current primary focus of the laboratory is the identification of the mechanisms responsible for limiting PTH clinical efficacy or its anabolic window.  Multiple approaches are brought to bear on this problem including the use of genetically modified mice, primary cell culture of mesenchymal stem cells, osteoprogenitors, and mature osteoblasts.  Skeletal phenotypes are analyzed using DXA, uCT, and bone histomorphometry. The molecular methodologies utilized for identifying signal transduction, transcription, and translation pathways activated during the closing of the anabolic window include ChIP-seq, qRT-PCR, Western blotting, immunoprecipitations, mass spectrometry, and cell transfection/immortalization.  Students participating in the Bidwell lab are trained to identify and develop an original and significant research question/hypothesis related to the overarching program.

  • Professional Organizations
    American Association for the Advancement of Science
    American Chemical Society
    American Society for Bone and Mineral Research
    American Society of Cell Biology

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