The overarching goals of research in the Schlecht Lab is to develop new clinical diagnostics for ACL injury prevention in adolescent and young adult recreational and competitive athletes, and to improve primary ACL reconstruction outcomes in this young patient population to mitigate early-onset osteoarthritis.
To pursue these endeavors, the lab has developed novel in vivo rodent models that allow for experimental outcomes to then be translated back to multi-institutional human cadaveric and patient research collaborations with University of Michigan and Monash University.
Moreover, the lab actively collaborates with clinicians at the Indiana Hand to Shoulder Clinic to investigate the mechanical integrity of novel digital and forearm nerve repairs; and clinicians at Purdue University and IU School of Medicine to investigate biomarkers for early collagen degradation of both the ACL and articular cartilage from synovial and circulating biofluid in the rodent model and total hip and knee arthroplasty patients.