Jay L. Hess, MD, PhD, MHSA
Executive Vice President for University Clinical Affairs
Dean, School of Medicine
Director, Indiana Statewide Medical Education System
Walter J. Daly Professor
Professor of Pathology & Laboratory Medicine
Professor of Medicine
Adjunct Professor, School of Public Health
Bio
Jay L. Hess, MD, PhD, MHSA, joined Indiana University School of Medicine in 2013 as its 10th dean.
He is responsible for the largest medical school in the United States, with nine campuses, more than 2,000 students, and nearly 7,200 full-time, part-time and volunteer faculty. In addition, he serves as one of four executive vice presidents of Indiana University and is charged with guiding the university’s clinical affairs strategy.
Since becoming dean, he has overseen a 125 percent increase in research funding from the National Institutes of Health, led the school through a comprehensive curriculum reform and successful reaccreditation, and strengthened the relationship with IU Health, its primary clinical partner and one of the nation’s premier academic medical centers. A physician-scientist, Hess is driven to improve care for patients and is guided by a commitment to transforming health in Indiana and around the world.
IU School of Medicine’s major initiatives under Hess’ leadership have included:
- Leading the charge to safely return students, faculty and staff to Indiana University campuses statewide after the unprecedented suspension of most in-person research and instruction at the start of the COVID-19 health crisis
- Enacting a single curriculum that includes interprofessional education and the opportunity to pursue scholarly concentrations on all campuses
- Investing in new educational and research facilities across the state
- Moving over 65 independent physician groups into a single faculty group practice, IU Health Physicians, to improve delivery of care and strengthen the alignment of clinical, education and research missions
- Implementing the IU Precision Health Initiative, a bold plan to develop new therapies and improve outcomes for patients with multiple myeloma, triple negative breast cancer, diabetes, childhood sarcoma and Alzheimer’s disease
- Bringing leading-edge therapies to Indiana, including genomically-guided therapies and CAR-T immunotherapy
- Securing prestigious Comprehensive status for the Indiana University Melvin and Bren Simon Cancer Center from the National Cancer Institute
- Expanding residency positions to increase the number of physicians who train and practice in Indiana
- Recruiting top-flight leaders, including 21 new department chairs and five research center and institute directors, both from within IU School of Medicine and from other top tier institutions
- Advancing diversity, inclusiveness and wellness of the faculty, staff and learners
- Raising over $1.7 billion as part of For All: The Indiana University Bicentennial Campaign with a focus on endowing chairs, professorships and scholarships
- Developing institution-wide strategic plans in 2014, 2018 and 2022
Education and Career Highlights
Hess earned his medical and doctorate degrees from the Johns Hopkins University School of Medicine and completed residency training in anatomic pathology and fellowships in hematopathology and surgical pathology at Brigham and Women’s Hospital. He holds a certificate in business administration from The Wharton School of the University of Pennsylvania, and a master’s degree in health services administration from the University of Michigan School of Public Health.
Before moving to Indiana, Hess served for eight years as the Carl V. Weller Professor and chair of the Department of Pathology and professor of pathology and internal medicine at the University of Michigan. He previously served as director of hematopathology at the University of Pennsylvania and as assistant professor of pathology at Washington University School of Medicine.
Year | Degree | Institution |
---|---|---|
2012 | MHSA | University of Michigan |
1989 | MD | Johns Hopkins University |
1989 | PhD | Johns Hopkins University |
1982 | BA | Johns Hopkins University |
A board-certified Hematopathologist and author of more than 100 scientific papers and book chapters, Dr. Hess is considered one of the nation’s leaders in the epigenetics of leukemia. His laboratory has done some of the most seminal work on the mechanisms of transformation by the mixed-lineage leukemia protein MLL and its downstream targets, the HOX proteins. While Chair at Michigan, Dr. Hess assembled and led an interdisciplinary research team working to develop epigenetically targeted therapeutics for acute leukemia. He continues to run an active NIH-funded research laboratory.
In 2007, Dr. Hess helped establish the Michigan Center for Translational Pathology led by Dr. Arul Chinnaiyan, one of the leading research centers for biomarker discovery in the nation. He created one of the first pathology informatics divisions in the nation and led the University of Michigan Health Care System strategy implementation in personalized medicine.
Collins CT; Hess JL; Current opinion in hematology 2016 Jul
Zhou B; Wang J; Lee SY; Xiong J; Bhanu N; Guo Q; Ma P; Sun Y; Rao RC; Garcia BA; Hess JL; Dou Y; Molecular cell 2016 Apr 12
Cohen OS; Weickert TW; Hess JL; Paish LM; McCoy SY; Rothmond DA; Galletly C; Liu D; Weinberg DD; Huang XF; Xu Q; Shen Y; Zhang D; Yue W; Yan J; Wang L; Lu T; He L; Shi Y; Xu M; Che R; Tang W; Chen CH; Chang WH; Hwu HG; Liu CM; Liu YL; Wen CC; Fann CS; Chang CC; Kanazawa T; Middleton FA; Duncan TM; Faraone SV; Weickert CS; Tsuang MT; Glatt SJ; Molecular psychiatry 2015 Sep 8
Hess JL; Kawaguchi DM; Wagner KE; Faraone SV; Glatt SJ; American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2015 Sep 14
Borkin D; He S; Miao H; Kempinska K; Pollock J; Chase J; Purohit T; Malik B; Zhao T; Wang J; Wen B; Zong H; Jones M; Danet-Desnoyers G; Guzman ML; Talpaz M; Bixby DL; Sun D; Hess JL; Muntean AG; Maillard I; Cierpicki T; Grembecka J; Cancer cell 2015 Mar 26
Collins CT; Hess JL; Oncogene 2015 Jun 1
Hess JL; Quinn TP; Akbarian S; Glatt SJ; American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2015 Jan
Murai MJ; Pollock J; He S; Miao H; Purohit T; Yokom A; Hess JL; Muntean AG; Grembecka J; Cierpicki T; Blood 2014 Oct 10
Collins C; Wang J; Miao H; Bronstein J; Nawer H; Xu T; Figueroa M; Muntean AG; Hess JL; Proceedings of the National Academy of Sciences of the United States of America 2014 Jun 23
Cao F; Townsend EC; Karatas H; Xu J; Li L; Lee S; Liu L; Chen Y; Ouillette P; Zhu J; Hess JL; Atadja P; Lei M; Qin ZS; Malek S; Wang S; Dou Y; Molecular cell 2014 Jan 2
Shen C; Jo SY; Liao C; Hess JL; Nikolovska-Coleska Z; The Journal of biological chemistry 2013 Sep 1
Hess JL; Glatt SJ; American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013 Oct 4
Muntean AG; Chen W; Jones M; Granowicz EM; Maillard I; Hess JL; Blood 2013 Jul 30
Maethner E; Garcia-Cuellar MP; Breitinger C; Takacova S; Divoky V; Hess JL; Slany RK; Cell reports 2013 Apr 25
Wang J; Muntean AG; Wu L; Hess JL; The Journal of biological chemistry 2012 Nov 5
Akalin A; Garrett-Bakelman FE; Kormaksson M; Busuttil J; Zhang L; Khrebtukova I; Milne TA; Huang Y; Biswas D; Hess JL; Allis CD; Roeder RG; Valk PJ; Löwenberg B; Delwel R; Fernandez HF; Paietta E; Tallman MS; Schroth GP; Mason CE; Melnick A; Figueroa ME; PLoS genetics 2012 Jun 21
Grembecka J; He S; Shi A; Purohit T; Muntean AG; Sorenson RJ; Showalter HD; Murai MJ; Belcher AM; Hartley T; Hess JL; Cierpicki T; Nature chemical biology 2012 Jan 29
Tomlins S; Robinson D; Penny RJ; Hess JL; Clinics in laboratory medicine 2012 Dec
Muntean AG; Hess JL; Annual review of pathology 2011 Oct 17
Huang Y; Sitwala K; Bronstein J; Sanders D; Dandekar M; Collins C; Robertson G; MacDonald J; Cezard T; Bilenky M; Thiessen N; Zhao Y; Zeng T; Hirst M; Hero A; Jones S; Hess JL; Blood 2011 Nov 9
Hess JL; Hsieh CH; Brothers SM; Hall MB; Darensbourg MY; Journal of the American Chemical Society 2011 Nov 29
Tan J; Jones M; Koseki H; Nakayama M; Muntean AG; Maillard I; Hess JL; Cancer cell 2011 Nov 15
Jo SY; Granowicz EM; Maillard I; Thomas D; Hess JL; Blood 2011 Feb 25
Wang J; Muntean AG; Hess JL; Blood 2011 Dec 15
Hess JL; Hsieh CH; Reibenspies JH; Darensbourg MY; Inorganic chemistry 2011 Aug 8
Monroe SC; Jo SY; Sanders DS; Basrur V; Elenitoba-Johnson KS; Slany RK; Hess JL; Experimental hematology 2010 Sep 18
Sanders DS; Muntean AG; Hess JL; Leukemia research 2010 Oct 16
Tan J; Muntean AG; Hess JL; Oncotarget 2010 Oct
Betz BL; Hess JL; Archives of pathology & laboratory medicine 2010 Oct
Hess JL; Archives of pathology & laboratory medicine 2010 Oct
Muntean AG; Tan J; Sitwala K; Huang Y; Bronstein J; Connelly JA; Basrur V; Elenitoba-Johnson KS; Hess JL; Cancer cell 2010 Jun 15
Fisher CL; Pineault N; Brookes C; Helgason CD; Ohta H; Bodner C; Hess JL; Humphries RK; Brock HW; Blood 2009 Oct 27
Fisher CL; Lee I; Bloyer S; Bozza S; Chevalier J; Dahl A; Bodner C; Helgason CD; Hess JL; Humphries RK; Brock HW; Developmental biology 2009 Oct 13
Green KN; Hess JL; Thomas CM; Darensbourg MY; Dalton transactions (Cambridge, England : 2003) 2009 Mar 2
Caslini C; Connelly JA; Serna A; Broccoli D; Hess JL; Molecular and cellular biology 2009 Jun 15
Hess JL; Archives of pathology & laboratory medicine 2009 Jun
Muntean AG; Hess JL; The American journal of pathology 2009 Aug 28
Maillard I; Hess JL; Advances in experimental medicine and biology 2009
Milne TA; Zhao K; Hess JL; Methods in molecular biology (Clifton, N.J.) 2009
Muntean AG; Giannola D; Udager AM; Hess JL; Blood 2008 Sep 16
Sitwala KV; Dandekar MN; Hess JL; International journal of clinical and experimental pathology 2008 Mar 30
Muntean AG; Hess JL; Cancer cell 2008 Jun
Hess JL; Conder HL; Green KN; Darensbourg MY; Inorganic chemistry 2008 Feb 9
Mueller D; Bach C; Zeisig D; Garcia-Cuellar MP; Monroe S; Sreekumar A; Zhou R; Nesvizhskii A; Chinnaiyan A; Hess JL; Slany RK; Blood 2007 Sep 12
Hess JL; Porsch EA; Shertz CA; Boyle MD; Journal of microbiological methods 2007 May 5
Dou Y; Hess JL; International journal of hematology 2007 Dec 4
Caslini C; Yang Z; El-Osta M; Milne TA; Slany RK; Hess JL; Cancer research 2007 Aug 1
Crawford BD; Hess JL; ACS chemical biology 2006 Sep 19
Chen YX; Yan J; Keeshan K; Tubbs AT; Wang H; Silva A; Brown EJ; Hess JL; Pear WS; Hua X; Proceedings of the National Academy of Sciences of the United States of America 2006 Jan 13
Hess JL; Boyle MD; Proteomics 2006 Jan
Hess JL; Bittner CB; Zeisig DT; Bach C; Fuchs U; Borkhardt A; Frampton J; Slany RK; Blood 2006 Feb 28
Sitwala KV; Hess JL; Cancer cell 2006 Apr
Boyle MD; Hess JL; Nuara AA; Buller RM; Methods (San Diego, Calif.) 2006 Apr
Milne TA; Dou Y; Martin ME; Brock HW; Roeder RG; Hess JL; Proceedings of the National Academy of Sciences of the United States of America 2005 Sep 30
Coyle EM; Blazer LL; White AA; Hess JL; Boyle MD; Applied microbiology and biotechnology 2005 Oct 27
Dou Y; Milne TA; Tackett AJ; Smith ER; Fukuda A; Wysocka J; Allis CD; Chait BT; Hess JL; Roeder RG; Cell 2005 Jun 17
Milne TA; Hughes CM; Lloyd R; Yang Z; Rozenblatt-Rosen O; Dou Y; Schnepp RW; Krankel C; Livolsi VA; Gibbs D; Hua X; Roeder RG; Meyerson M; Hess JL; Proceedings of the National Academy of Sciences of the United States of America 2005 Jan 7
Wang J; Iwasaki H; Krivtsov A; Febbo PG; Thorner AR; Ernst P; Anastasiadou E; Kutok JL; Kogan SC; Zinkel SS; Fisher JK; Hess JL; Golub TR; Armstrong SA; Akashi K; Korsmeyer SJ; The EMBO journal 2005 Jan 6
Hess JL; Blazer L; Romer T; Faber L; Buller RM; Boyle MD; Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005 Feb 5
Milne TA; Martin ME; Brock HW; Slany RK; Hess JL; Cancer research 2005 Dec 15
Tarakanova VL; Suarez F; Tibbetts SA; Jacoby MA; Weck KE; Hess JL; Speck SH; Virgin HW 4th; Journal of virology 2005 Dec
Zeisig DT; Bittner CB; Zeisig BB; García-Cuéllar MP; Hess JL; Slany RK; Oncogene 2005 Aug 18
Hess JL; Trends in molecular medicine 2004 Oct
Hess JL; Hug BA; Proceedings of the National Academy of Sciences of the United States of America 2004 Nov 30
Hess JL; Atha DH; Xu JF; Highsmith WE Jr; Electrophoresis 2004 Jun
Zeisig BB; Milne T; García-Cuéllar MP; Schreiner S; Martin ME; Fuchs U; Borkhardt A; Chanda SK; Walker J; Soden R; Hess JL; Slany RK; Molecular and cellular biology 2004 Jan
Hughes CM; Rozenblatt-Rosen O; Milne TA; Copeland TD; Levine SS; Lee JC; Hayes DN; Shanmugam KS; Bhattacharjee A; Biondi CA; Kay GF; Hayward NK; Hess JL; Meyerson M; Molecular cell 2004 Feb 27
Mitra-Kaushik S; Harding JC; Hess JL; Ratner L; Blood 2004 Apr 15
Hess JL; Critical reviews in eukaryotic gene expression 2004
Martin ME; Milne TA; Bloyer S; Galoian K; Shen W; Gibbs D; Brock HW; Slany R; Hess JL; Cancer cell 2003 Sep
Atha DH; Miller K; Sanow AD; Xu J; Hess JL; Wu OC; Wang W; Srivastava S; Highsmith WE; Electrophoresis 2003 Jan
Hess JL; Cancer investigation 2003 Apr
Hess JL; Clark LS; Moore MM; Environmental and molecular mutagenesis 2003
Milne TA; Briggs SD; Brock HW; Martin ME; Gibbs D; Allis CD; Hess JL; Molecular cell 2002 Nov
Hess JL; American journal of clinical pathology 2002 Mar
Hess JL; Highsmith WE Jr; Clinical chemistry 2002 Jan
Hess JL; Kossev P; Cancer investigation 2002
Wang YL; Bagg A; Pear W; Nowell PC; Hess JL; Genes, chromosomes & cancer 2001 Oct
Portis T; Grossman WJ; Harding JC; Hess JL; Ratner L; Journal of virology 2001 Mar
Zhang T; Westervelt P; Hess JL; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000 Sep
Khariwala SS; Litman DA; McQuone SJ; Hess JL; Thaler ER; Archives of otolaryngology--head & neck surgery 2000 Nov
Caslini C; Alarcòn AS; Hess JL; Tanaka R; Murti KG; Biondi A; Leukemia 2000 Nov
Caslini C; Shilatifard A; Yang L; Hess JL; Proceedings of the National Academy of Sciences of the United States of America 2000 Mar 14
Thorson P; Hess JL; Archives of pathology & laboratory medicine 2000 Mar
DiMartino JF; Miller T; Ayton PM; Landewe T; Hess JL; Cleary ML; Shilatifard A; Blood 2000 Dec 1
Movsas TZ; Balcer LJ; Eggenberger ER; Hess JL; Galetta SL; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2000 Dec
van Dyk LF; Hess JL; Katz JD; Jacoby M; Speck SH; Virgin HW IV; Journal of virology 1999 Jun
Kaleem Z; Watson MS; Zutter MM; Blinder MA; Hess JL; American journal of clinical pathology 1999 Jul
Hanson RD; Hess JL; Yu BD; Ernst P; van Lohuizen M; Berns A; van der Lugt NM; Shashikant CS; Ruddle FH; Seto M; Korsmeyer SJ; Proceedings of the National Academy of Sciences of the United States of America 1999 Dec 7
Yu BD; Hanson RD; Hess JL; Horning SE; Korsmeyer SJ; Proceedings of the National Academy of Sciences of the United States of America 1998 Sep 1
Hess JL; Korsmeyer SJ; Nature genetics 1998 Nov
Naughton MJ; Hess JL; Zutter MM; Bartlett NL; Cancer 1998 Mar 15
Hess JL; American journal of clinical pathology 1998 Mar
Hess JL; American journal of clinical pathology 1998 Jan
Zutter MM; Hess JL; American journal of clinical pathology 1998 Apr
Hess JL; Yu BD; Li B; Hanson R; Korsmeyer SJ; Blood 1997 Sep 1
Mitton KP; Hess JL; Bunce GE; Current eye research 1997 Oct
Lin Y; Govindan R; Hess JL; American journal of clinical pathology 1997 Feb
Kaleem Z; Wakoff AR; Smith RP; Hess JL; Archives of pathology & laboratory medicine 1996 Jun
Hess JL; Zutter MM; Castleberry RP; Emanuel PD; American journal of clinical pathology 1996 Feb
Hess JL; Mitton KP; Bunce GE; Ophthalmic research 1996
Yu BD; Hess JL; Horning SE; Brown GA; Korsmeyer SJ; Nature 1995 Nov 30
Sires UI; Mallory SB; Hess JL; Keating JP; Bloomberg G; Dehner LP; Pediatric dermatology 1995 Dec
Linette GP; Hess JL; Sentman CL; Korsmeyer SJ; Blood 1995 Aug 15
Mitton KP; Hess JL; Bunce GE; Investigative ophthalmology & visual science 1995 Apr
Hess JL; Bodis S; Pinkus G; Silver B; Mauch P; Cancer 1994 Jul 15
Wang Z; Bunce GE; Hess JL; Current eye research 1993 Mar
Shivdasani RA; Hess JL; Skarin AT; Pinkus GS; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993 Apr
Sheng WS; Chevone BI; Hess JL; Environmental pollution (Barking, Essex : 1987) 1993
Madamanchi NR; Anderson JV; Alscher RG; Cramer CL; Hess JL; Plant physiology 1992 Sep
Huang LL; Zhang CY; Hess JL; Bunce GE; Experimental eye research 1992 Nov
Wang Z; Hess JL; Bunce GE; Current eye research 1992 Jul
Wang Z; Hess JL; Bunce GE; Investigative ophthalmology & visual science 1992 Jul
Anderson JV; Chevone BI; Hess JL; Plant physiology 1992 Feb
Calvin HI; von Hagen S; Hess JL; Patel SA; Fu SC; Experimental eye research 1992 Apr
Calvin HI; Medvedovsky C; David JC; Broglio TM; Hess JL; Fu SC; Worgul BV; Investigative ophthalmology & visual science 1991 May
Anderson JV; Hess JL; Chevone BI; Plant physiology 1990 Nov
Huang LL; Hess JL; Bunce GE; Current eye research 1990 Nov
Gabuzda DH; Hess JL; Small JA; Clements JE; Molecular and cellular biology 1989 Jun
Hess JL; Small JA; Clements JE; Journal of virology 1989 Jul
Foster JG; Cress WD; Wright SF; Hess JL; Plant physiology 1987 Apr
Griffin DE; Hess JL; Moench TR; Toxicologic pathology 1987
Hess JL; Pyper JM; Clements JE; Journal of virology 1986 Nov
Griffin DE; Hess JL; Journal of immunology (Baltimore, Md. : 1950) 1986 Mar 1
Hess JL; Clements JE; Narayan O; Science (New York, N.Y.) 1985 Aug 2
Bunce GE; Hess JL; Davis D; Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1984 Sep
Clifford CB; Jaeger JJ; Moe JB; Hess JL; Military medicine 1984 Sep
Bunce GE; Hess JL; Batra R; Current eye research 1984 Feb
Kelso TB; Herbert WG; Gwazdauskas FC; Goss FL; Hess JL; Journal of applied physiology: respiratory, environmental and exercise physiology 1984 Aug
Wolinsky JS; Waxham MN; Hess JL; Townsend JJ; Baringer JR; Clinical and experimental immunology 1982 May
Bunce GE; Hess JL; Experimental eye research 1981 Nov
Hess JL; Haynes LR; Bunce GE; Experimental eye research 1981 Mar
Foster JG; Hess JL; Plant physiology 1980 Sep
Penk WE; Robinowitz R; Woodward WA; Hess JL; The International journal of the addictions 1980 Apr
Hess JL; Veterinary medicine, small animal clinician : VM, SAC 1979 Oct
Hess JL; Raflo CP; Laboratory animal science 1979 Jun
Penk WE; Woodward WA; Rbinowitz R; Hess JL; Journal of abnormal psychology 1978 Oct
Bunce GE; Hess JL; Fillnow GM; Experimental eye research 1978 Apr
Hess JL; Pallansch MA; Harich K; Bunce GE; Analytical biochemistry 1977 Dec
Bunce GE; Hess JL; The Journal of nutrition 1976 Feb
Reed RE; Hess JL; The Journal of biological chemistry 1975 Jun 25
Love JW; Hess JL; Veterinary medicine, small animal clinician : VM, SAC 1975 Jul
Hess JL; Rudy RL; Veterinary medicine, small animal clinician : VM, SAC 1974 Nov
Hess JL; Reed RE; Archives of biochemistry and biophysics 1972 Nov
Nelson EB; Tolbert NE; Hess JL; Plant physiology 1969 Jan
Denenberg VH; Rosenberg KM; Paschke R; Hess JL; Zarrow MX; Endocrinology 1968 Oct
Ji TH; Hess JL; Benson AA; Biochimica et biophysica acta 1968 Jun 11
Hess JL; Tolbert NE; Pike LM; Planta 1967 Sep
Hess JL; Tolbert NE; Plant physiology 1967 Mar
Hess JL; Tolbert NE; Plant physiology 1967 Aug
Tolbert NE; Hess JL; The Journal of biological chemistry 1966 Dec 10
Hess JL; Tolbert NE; The Journal of biological chemistry 1966 Dec 10
SIMON S; HESS JL; Psychological reports 1965 Apr
HESS JL; LOMBARD CF; The Journal of aviation medicine 1958 Jan
Desc: President's Medal
Scope: University
Date: 1905-07-15
Desc: Elected Member
Scope: National
Date: 1905-06-28