Dr. Spinola received a B.A. from Brown University in 1974 (Biology) and a M.D. from Georgetown University in 1978. He completed a residency in Internal Medicine and Pediatrics at the University of North Carolina at Chapel Hill in 1982 and served in the National Health Service Corps from 1982-1984. He completed a fellowship in Adult and Pediatric Infectious Diseases at the University of North Carolina in 1987, where he trained in Janne Cannon's laboratory and was funded by a NRSA grant. From 1987 to 1993, Dr. Spinola was at the State University of New York at Buffalo as an Assistant and then Associate Professor in the Department of Medicine. He came to Indiana University in 1993 to join the Division of Infectious Diseases in the Department of Medicine and was named the Division Director in 1995. In 1999, Dr. Spinola was named the first David H. Jacobs Professor of Infectious Diseases; he served as Chair of the Department of Microbiology and Immunology from 2010-2019 and is currently a Professor of Microbiology and Immunology, Medicine, and Pathology and Laboratory Medicine. He has been NIH funded from 1990 through 2024. He is a member of the American Society for Clinical Investigation and a Fellow in the American Academy of Microbiology and in the Infectious Diseases Society of America. He served for 2 terms as a Member and Chair of the Microbiology and Infectious Diseases Review Committee, a standing study section of NIAID that reviews training grants and career development awards. He has served as primary mentor for 7 graduate students, 7 ID fellows, 7 PhD postdoctoral fellows, 20 short term trainees, and 5 faculty members for Developmental Awards, K08 or K22 awards. He was the recipient of the Indiana University School of Medicine 2017 Basic Science Excellence in Faculty Mentoring Award.