63227-Peng, Gang

Gang Peng, PhD

Assistant Professor of Medical & Molecular Genetics

MS 502
Indianapolis, IN
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Dr. Peng is an assistant professor in the Department of Medical and Molecular Genetics, Indiana University School of Medicine (IUSM). He is the director of Bioinformatics in Indiana Center for Musculoskeletal Health. Dr. Peng received his Ph.D degree mentored by Dr. Wenyi Wang from MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences. He finished his postdoctoral training under the supervision of Drs. Hongyu Zhao and Curt Scharfe in Yale School of Public Health and Yale School of Medicine.  He continued his research as a research faculty at Yale and joined IUSM in September 2022.

Key Publications

Lopez De Rodas M, Wang Y, Peng G, Gu J, Mino-Kenudson M, Riess JW, Velcheti V, Hellmann M, Gainor JF, Zhao H, Schalper KA. 2023. Objective analysis and clinical significance of the spatial tumor infiltrating lymphocyte patterns in non-small cell lung cancer (NSCLC). Clin Cancer Res.

Xie Y, Peng G, Zhao H, Scharfe C. 2023. Association of Maternal Age and Blood Markers for Metabolic Disease in Newborns. Metabolites, 14(1), p.5.

Lin Y, Peng G, Bruner DW, Miller AH, Saba NF, Higgins KA, Shin DM, Claussen H, Johnston HR, Houser MC, Wommack EC, Xiao C. 2023. Associations of differentially expressed genes with psychoneurological symptoms in patients with head and neck cancer: A longitudinal study. J Psychosom Res. 175:111518.

Xiao C, Fedirko V, Claussen H, Richard Johnston H, Peng G, Paul S, Maner-Smith KM, Higgins KA, Shin DM, Saba NF, Wommack EC, Bruner DW, Miller AH. 2023. Circulating short chain fatty acids and fatigue in patients with head and neck cancer: A longitudinal prospective study. Brain Behav Immun. 113:432-443.

Prideaux M, Smargiassi A, Peng G, Brotto M, Robling AG, Bonewald LF. 2023. L-BAIBA Synergizes with Sub-Optimal Mechanical Loading to Promote New Bone Formation. JBMR Plus. 7(6):e10746.

Peng G*, Zhou Q*, Chai H, Wen J, Zhao H, Taylor HS, Jiang YH, Li P. Estimation on risk of spontaneous abortions by genomic disorders from a meta-analysis of microarray results on large case series of pregnancy losses. 2023. Mol Genet Genomic Med. 11(8):e2181. *authors contributed equally

Habet V, Li N, Qi J, Peng G, Charkoftaki G, Vasiliou V, Sharma L, Pober JS, Dela Cruz C, Yan X, Pierce RW. 2023. Integrated Analysis of Tracheobronchial Fluid from Before and After Cardiopulmonary Bypass Reveals Activation of the Integrated Stress Response and Altered Pulmonary Microvascular Permeability. Yale J Biol Med. 96(1):23-42.

Mak J*, Peng G*, Le A, Gandotra N, Enns GM, Scharfe C, Cowan TM. 2023. Validation of a targeted metabolomics panel for improved second-tier newborn screening. J Inherit Metab Dis. 46(2):194-205. *authors contributed equally

Qian DC, Ulrich BC, Peng G, Zhao H, Conneely KN, Miller AH, Bruner DW, Eldridge RC, Wommack EC, Higgins KA, Shin DM. 2023. Outcomes Stratification of Head and Neck Cancer Using Pre-and Posttreatment DNA Methylation From Peripheral Blood. International Journal of Radiation Oncology* Biology* Physics. 115(5):1217-1228.

Peng G, Pakstis AJ, Gandotra N, Cowan TM, Zhao H, Kidd KK, Scharfe C., 2022, Metabolic diversity in human populations and correlation with genetic and ancestral geographic distances. Molecular Genetics and Metabolism.

Peng G*, Xi Y*, Bellini C, Kien P, Zhuang Z, Yan Q, Jia M, Wang G, Krishnan-Sarin S, Tang M, Zhao H, Wang H., 2022, Nicotine Dose-Dependent Epigenomic-Wide DNA Methylation changes in the mice with long-term electronic cigarette exposure. American Journal of Cancer Research. 12(8):3679-92. *authors contributed equally

Peng G, Zhang Y, Zhao H, Scharfe C., 2022, dbRUSP: a database of investigating influence of clinical variables to metabolic levels in newborn screening. International Journal of Neonatal Screening. 8(3):48.

AlOlaby RR, Zafarullah M, Barboza M, Peng G, Varian BJ, Erdman SE, Lebrilla C, Tassone F., 2022, Differential Methylation Profile in Fragile X Syndrome-Prone Offspring Mice after in Utero Exposure to Lactobacillus Reuteri. Genes. 13(8):1300.

Peng, G., Chai, H., Ji, W., Lu, Y., Wu, S., Zhao, H., Li, P., Hu, Q., 2021, Correlating genomic copy number alterations with clinicopathologic findings in 75 cases of hepatocellular carcinoma. BMC Medical Genomics, 14.1 (2021): 1-9.

Xiao, C., Beitler, J., Peng, G., Levine, M., Conneely, K., Zhao, H., Felger, J., Wommack, E., Chico, C., Jeon, S., Higgins, K., Shin, D., Saba, N., Burtnes, B., Bruner, D., Miller, A., 2021, Epigenetic age acceleration, inflammation, and fatigue in patients undergoing radiation therapy for head and neck cancer: a longitudinal study. Cancer, 127(18):3361-3371.

Peng, G.,
Tang, Y., Cowan, T.M., Zhao, H. and Scharfe, C., 2021. Timing of newborn blood collection alters metabolic disease screening performance. Frontiers in Pediatrics, 8.

Xiao, C., Miller, A.H., Peng, G., Levine, M.E., Conneely, K.N., Zhao, H., Eldridge, R.C., Wommack, E.C., Jeon, S., Higgins, K.A. and Shin, D.M., 2021. Association of epigenetic age acceleration with risk factors, survival, and quality of life in patients with head and neck cancer. International Journal of Radiation Oncology* Biology* Physics.

Full List of Publication

Titles & Appointments

  • Assistant Professor of Medical & Molecular Genetics
  • Director of Bioinformatics Indiana Center for Musculoskeletal Health
  • Education
    2015 PhD University of Texas Health Science Center at Houston
    2005 BS Fudan University
  • Research
    Developing bioinformatics methods and software to analyze different kinds of omics data, with a particular emphasis on epigenomics (DNA Methylation)

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