61508-Zhang, Dongwei

Dongwei Zhang, MD, PhD

Associate Professor of Clinical Pathology & Laboratory Medicine

IU Health Pathology Laboratory
350 W 11th Street, Rm 4062

Indianapolis, IN 46202
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Dr. Dongwei Zhang is currently an Associate Professor and Director of Gastrointestinal and Liver Pathology Fellowship at the Department of Pathology and Laboratory Medicine at Indiana University. He is a surgical pathologist who specializes in gastrointestinal and liver pathology. He completed his residency in Anatomic and Clinical Pathology at the Mount Sinai Hospital/Medical Center at New York city, followed by Surgical Pathology fellowship at Columbia University Medical Center and Gastrointestinal and Liver Pathology fellowship at University of Florida. Before he joined pathology residency, he also obtained his Ph.D. in Tumor Genetics and Biology and worked as postdoctoral fellow and instructor at MD Anderson Cancer Center.

Key Publications

  1. Gonzalez IA, Saeed O, Mustafa M, Segura SE, Collins K, Hou T, Messa H, Lee SM, Zhang D, Lin J, Cummings OW. Incidental Findings During Donor Liver Assessment: single center experience. Annals of Diagnostic Pathology. 2024 Apr:69:152266. PMID: 38266545
  2. Hou T, Abu-Salah A, Cummings OW, Halum S, Mesa H, Zhang D*. Amyloid Deposition in the Upper Aerodigestive Tract, A Single Institute Experience. Ear, Nose & Throat Journal. First published online July 28, 2023. https://doi.org/10.25384/SAGE.c.6766214.v1
  3. Liao X, Oltvai ZN, Zhang D*. Synchronous Triple Thyroid Neoplasms With Unique Molecular Alterations: A Rare Case Report. Human Pathology Reports. 2023;33:300709. https://doi.org/10.1016/j.hpr.2023.300709
  4. Rex DK, Lahr RE, Guardiola JJ, Dewitt JM, Zhang D*. Characterization of endoscopic features and histology of a distinct mucosal transition zone on the ileocecal valve. Gastrointest Endosc. 2023 Mar 31;S0016-5107(23)00361-9. PMID: 37004817.
  5. Liao X, Lai J, Lin J, Zhang D*. Primary and Secondary Angiosarcomasof the Liver: A Multi-institutional Study of 32 Cases. Human pathology. 2023;137:10-17. PMID: 37054784
  6. Liu X, Zhang D, Liao X. Paget cells of the esophagus: A clinicopathologic and immunohistochemical study of 10 cases. Pathology - Research and Practice. 2023 Jan 24;242:154345. PMID: 36708601
  7. Lahr RE, DeWitt JM, Zhang D, Rex DK. Assessment of Submucosal Distortion and Mass Effect Seen at Follow-up After Colorectal Endoscopic Mucosal Resection with ORISE. Gastrointestinal Endoscopy. 2022 Oct;96(4):679-682. PMID: 35550794
  8. Liao X, Zhang D*, Groove pancreatitis due to periampullary gangliocytic paraganglioma with lymph node metastasis. Pathology. 2022 Oct 7;S0031-3025(22)00268-9. PMID: 36328810
  9. Weldemichael W, Zhang D, Lin J. Histopathological Evaluation of Recurrent Primary Biliary Cholangitis after Liver Transplantation. Journal of Clinical and Translational Pathology. 2022; 2(3):91-99. doi: 10.14218/JCTP.2022.00021
  10. Chen IY, Giampoli E, Zhang D*. Ameloblastic Carcinoma of the Maxilla: A Rare Case Report and Review of Literature from 1948 to 2021. International Journal of Surgical Pathology. 2022 Jun 6; 10668969221102542. PMID: 35668625
  11. Zhang D, Liao X. Pan-TRK Protein Expression and NTRK Gene Fusions in Primary Carcinomas of the Liver. Applied ImmunohistochemistryMolecular Morphology. 2022 Jul 1;30(6):435-440. PMID: 35587529
  12. Mahdi Z, Zhang D, Gonzalez RS. Accuracy of Risk-Stratifying Gastrointestinal Stromal Tumours Using Information Available During Biopsy. 2022 Jul;81(1):137-141. PMID: 35347745
  13. Zhang D, Love T, Hao Y, Liu J, Thung S, Fiel M, Whitney-Miller C, Liao X. Tumor Size, Not Small Vessel Invasion Predicts Survival in Patients With Hepatocellular Carcinoma. American Journal of Clinical Pathology. 2022 Feb 10;aqac001. PMID: 35142813
  14. Liao X, Zhang D*. HHLA2 immune checkpoint is a novel prognostic predictor in hepatocellular carcinoma. American Journal of Clinical Pathology. 2022 Jan 27;aqab221. PMID: 35084443
  15. Gonzalez IA, Fuller LD, Zhang X, Papke Jr DJ, Zhao L, Zhang D, Liao X, Liu X, Fiel MI, Zhang X. Development of a novel scoring system to differentiate amiodarone-induced liver injury from alcoholic steatohepatitis. American Journal of Clinical Pathology. 2022;157:434-442. PMID: 34596220
  16. Solomianko M, Chen IY, Srinivas K, Zhang D. Metastatic Pleomorphic Dermal Sarcoma Involving Tonsil and Thyroid: An Unusual Presentation. An International Journal of Otorhinolaryngology Clinic. 2021:10.5005/jp-journals-10003-1432
  17. Chen I, Zhang D, Velez M, Kovar, S, Liao X. Poorly differentiated neuroendocrine carcinomas of the gastrointestinal tract: A single-institute study of 43 cases. Pathology - Research and Practice. 2021;226:153614. PMID: 34555651.
  18. Liao X, Fulmer S, Zhang D*. Well-Differentiated Spindle Cell Liposarcoma of the Larynx: A Rare Case Report and Review of Literature. In Vivo. 2021;35:2779-2783. PMID: 34410968
  19. Liu X, Liao X, Zhang D*. Squamous Cell Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: Unusual Entity and Diagnostic Pitfalls. Cancer Diagnosis & Prognosis. 2021;1:279-283. DOI: 21873/cdp.10036
  20. Zhang D, Chen I, Liao X. Small Intestinal Adenocarcinomas Arising in Enteritis Cystica Profunda With Metaplasia: A Report of 2 Cases. Applied ImmunohistochemistryMolecular Morphology. 2021 Jun 16. PMID: 34132683.
  21. Li P, Zhang D, Zhou J, et al. Hepatic involvement by T-cell neoplasms: a clinicopathologic study of 40 cases. Human Pathology. 2020;106:1-12. PMID: 33010300
  22. Numbere N, Zhang D, Agostini-Vulaj D. A rare histologic subtype of hepatocellular carcinoma, sarcomatoid hepatocellular carcinoma: report of a case. Hepatic Oncology. 2020 Dec 29;8:HEP33. PMID34084452
  23. Katerji R, Liao X, Huber A, Zhang D*. An Unusual Case of HPV-Related Anorectal Adenocarcinoma with Progression to Perianal Paget’s Disease. International Journal of Surgical Pathology. 2020 Dec 24. PMID: 33356675
  24. Yin F, Saad M, Lin J, et al. Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer. Gastroenterology Report. 2020 Nov 24. DOI: 10.1093/gastro/goaa084
  25. Zhang D, Qi Y, Katerji R, Drage M, Huber A, Liao X. Malignant tumors in hernia sac: Clinicopathological and immunohistochemical studies of 21 cases at a single institution. Pathology International. 2020 Sep 17.PMID: 32940948

- Highlighted in MedPage Today on 10/13/2020. https://www.medpagetoday.com/meetingcoverage/cap/89087?xid=nl_mpt_confroundup_2020-10-16&eun=g11516132d41r

  1. Liao X, Zhang D. The 8th Edition American Joint Commission on Cancer (AJCC) Staging for Hepato-pancreato-biliary Cancer: A Review and Update. Archives of Pathology & Laboratory Medicine. 2020 Mar 30. DOI: 10.5858/arpa.2020-0032-RA. PMID: 32223559
  2. Zhang D, Li P, Szankasi P, Liao X. Mixed adenoneuroendocrine carcinoma of the gallbladder, amphicrine type: Case report and review of literature. Pathology – Research and Practice. 2020;216:152997. PMID: 32534704
  3. Yin F, Saad M, Xie H, Lin J, Jackson C, Ren B, Lawson C, Karamchandani DM, Bernabeu BQ, Jiang W, Dhir T, Zheng R, Schultz S, Zhang D, Thomas C, Zhang X, Lai J, Schild M, Zhang X and Liu X. Validation of AJCC 8th Edition of TNM Staging in Resected Distal Pancreatic Cancer. World Journal of Gastrointestinal Pharmacology and Therapeutics. 2020;11:25-39. PMID: 32550043
  4. Liao X, Liu, X, Fan X, Lai J, Zhang D*. Perianal Paget's disease: a clinicopathological and immunohistochemical study of 13 cases. Diagnostic pathology. 2020;15:29. PMID: 32209119

- Selected and highlighted in GIPS (Rodger C. Haggitt Gastrointestinal Pathology Society) “Journal Watch” in March and April in 2020

  1. Bell PD, Thung S, Weiss S, Levstik M, Zhang D, Liu X, Liao X. Hepatocellular Adenoma(s) Arising in Nodular Regenerative Hyperplasia in a Patient with Systemic Lupus Erythematosus. Pathology – Research and Practice. 2020;216:152770. PMID: 31810588
  2. Liao X, Fontanarosa JB, Zhang D*. Collision Tumor of a Squamous Cell Carcinoma and Adenoid Cystic Carcinoma in Mobile Tongue. Journal of Clinical Research and Medicine. 2020;3:1-3.
  3. Zhang D*, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X. Clinicopathologic features of Buschke-Löwenstein tumor: a multi-institutional analysis of 38 cases. Virchows Archiv. 2020;476:543-550. PMID: 31728626
  4. Zhang D, Hart J, Ding X, Zhang X, Feely M, Yassan L, Alpert L, Soldevila-Pico C, Zhang X, Liu X, Lai J. Histologic patterns of liver injury induced by anti-PD-1 therapy. Gastroenterology Report. 2020; 8:50-55. PMID: 32467761
  5. Liao X, Abu-Farsakh SH, Zhang D*. Sarcomatoid Renal Cell Carcinoma with Unusual Metastasis to the Small Intestine Manifesting as Perforated Appendicitis. In Vivo. 2019;33:2225-2228. PMID: 31662560
  6. Wang W, Lin E, Zhang D, Crane B. Onyx embolization material extrusion in the middle ear. Otology & Neurotology. 2019;40:e847-e849. PMID: 31356490
  7. Zhang D, Liao X, Tang Y, Meyer RG, Van Dyne DL, Liu X, Islam MN, Lai J. Warthin-like Mucoepidermoid Carcinoma of the Parotid Gland: Unusual Morphology and Diagnostic Pitfalls. Anticancer Research. 2019;39:3213-3217. PMID: 31177170
  8. Jin Z, Zhang D, Zhang Q, Lai J, Esnakula A, Kresek J, Gonzalo DH, Draganov PV, Xie H, Liu X. Desmoplasia and detached papillae in early esophageal adenocarcinoma: a histologic study on endoscopic submucosal dissection specimens. Gastroenterology Research. 2019;12:72-77. PMID: 31019616
  9. Hu M, Tang Y, Long G, Zhang D, Kresak JL, Lai J. Primary Extracranial Meningioma of Mastoid in a Patient with History of Skin Squamous Cell Carcinoma, Lung Adenocarcinoma and Prostatic Carcinoma. Anticancer Research. 2019;39:3197-3201. PMID: 31177167
  10. Lai J, Kresak JL, Cao D, Zhang D, Zhang S, Leon ME, Shenoy A, Liu W, Trevino J, Starostik P, Gonzalo DH, Wang H, Liu X, Fan X. Gastric Plexiform Fibromyxoma: A Great Mimic of Gastrointestinal Stromal Tumor (GIST) and Diagnostic Pitfalls. Journal of Surgical Research. 2019;239:76-82. PMID: 30822694
  11. Zhang D, Williams WD, Lai J. An Unusual Case of Cecal Mesenteric Dedifferentiated Liposarcoma Involving the Ileocolic Artery Resected by Right Hemicolectomy. Anticancer Research. 2019;39:487-490. PMID: 30591499
  12. Zhang D, Glover SC, Liu W, Liu X, Lai J. Small Bowel Pyogenic Granuloma with Cytomegalovirus Infection in a Patient with Crohn’s Disease (Report of a Case and Review of the Literature). In Vivo. 2019;33:251-254. PMID: 30587632
  13. Hu M, Liu W, Yin F, Zhang D, Liu X, Lai J. Liver Metastasis of Hepatoid Colonic Adenocarcinoma: A Rare and Unusual Entity with Poor Prognosis and Review of the Literature. Gastroenterology Research. 2018;11:430-435. PMID: 30627268
  14. Liu W, Zhang D, Tan SA, Liu X, Lai J. Sigmoid colon adenocarcinoma with isolated loss of PMS2 presenting in a patient with synchronous prostate cancer with intact MMR: diagnosis and analysis of the family pedigree. Anticancer Research. 2018;38:4847- PMID: 30061258
  15. Kai K, Iwamoto T, Zhang D, Shen L, Takahashi Y, Rao A, Thompson A, Sen S, Ueno CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer. Scientific Reports. 2018;8:9427.

Titles & Appointments

  • Associate Professor of Clinical Pathology & Laboratory Medicine
  • Education
    2018 Fellowship University of Florida College of Medicine
    2017 Fellowship Columbia University Medical Center
    2016 Residency The Mount Sinai Hospital
    2005 PhD Kumamoto University
    1995 MD China Medical University
  • Research
    Dr. Dongwei Zhang’s research includes studies on gastrointestinal, hepatocellular and pancreatobiliary carcinomas.
  • Professional Organizations
    American Society for Clinical Pathology
    Chinese American Pathologist Association
    College of American Pathologist
    Indiana Association of Pathologists
    Rodger C. Haggitt Gastrointestinal Pathology Society (GIPS)
    United States & Canadian Academy of Pathology
  • Board Certifications
    American Board of Pathology - Pathology-Anatomic/Pathology-Clinical*
  • Clinical Interests

    Gastrointestinal, pancreas, and hepatobiliary pathology
    Head & neck and endocrine pathology

  • Awards
    Org: American Society for Clinical Pathology
    Desc: Best case study award
    Scope: National
    Date: 2023-10-18
    Org: University of Rochester Medical Center
    Desc: Faculty Stormy Weather Award
    Scope: Department
    Date: 2021-12-01
    Org: Chinese American Pathologists Association Annual Meeting
    Desc: Best Abstract Award
    Scope: National
    Date: 2018-03-18
    Org: College of American Pathologists
    Desc: CAP '15 Top 5 Junior Member Abstract Program Award (First Place)
    Scope: National
    Date: 2015-10-04
    Org: The Mount Sinai Hospital
    Desc: Pathology Resident Research Scholarship
    Scope: Department
    Date: 2013-07-01
    Org: American Association for Cancer Research
    Desc: Bristol-Myers Squibb Oncology Award
    Scope: National
    Date: 2010-04-17
    Org: University of Texas MD Anderson Cancer Center
    Desc: Susan G. Komen for the Cure Postdoctoral Fellowship Award
    Scope: National
    Date: 2009-07-01
    Org: American Association for Cancer Research
    Desc: Avon Foundation Award
    Scope: National
    Date: 2004-03-27

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