After finishing the B.S from Hanoi University of Sciences, Hanoi, Vietnam, Dr. Tran went to KAIST, South of Korea, to pursuit his Ph.D. in stem cell biology. Then, as a postdoc, he joined Dr. Xinyang Zhao’s group, the University of Alabama at Birmingham, Alabama, U.S, to work intensively on cancer biology, biochemistry, and hematopoiesis. Inspired by the thriving of the CRISPR/Cas9 system, he moved to Klaus Rajewsky’s laboratory, Max Delbrück Center for Molecular Medicine, Berlin, Germany, to study hematopoiesis, lymphomagenesis, and immunity. Here, he has developed an efficient system to knock in and knock out genes in hematopoietic stem/progenitor cells (HSPCs) and induced pluripotent stem cells (iPSCs). This system can be broadly exploited to both modeling and developing gene therapy for blood disorders.
Dr. Tran joined the Department of Pediatrics at Indiana University in May 2021 to develop his independent research program aiming to study hematopoietic malignancies. His ultimate goal is to develop gene therapy and therapeutic approaches for blood disorders.