59597-Yadav, Amol
Faculty

Amol P. Yadav, PhD, MS, BE

Assistant Professor of Neurological Surgery

Address
NB 500B
Neuroscience Research Building

Indianapolis, IN

Bio

I am an Assistant Professor in the department of Neurological Surgery at Indiana University School of Medicine. The Yadav Lab is located at the IU Neuroscience Center. 

I completed my PhD in the Dept. of Biomedical Engineering at Duke University in the laboratory of Dr. Miguel Nicolelis - who is known for his expertise in brain-machine interfaces. As a neural engineer, during graduate school I developed methods for chronic spinal cord stimulation in rodent models of Parkinson's disease and refractory epilpepsy. During my postdoctoral training I conducted research in non-human primates and rodents and developed techniques such as closed-loop spinal cord stimulation, brain-spine interfaces, and generating artificial sensations using dorsal column stimulation. Prior to joining IU, I worked with surgeons at Duke Neurosurgery to develop hardware and software tools for translation of my work in human subjects.

Key Publications

Yadav, A.P., Li, S., Krucoff, M.O., Lebedev, M., Abd-El-Barr, M., Nicolelis, M.A.L. (2021) Generating artificial sensations with spinal cord stimulation in primates and rodents. Brain Stimulation,14, 4, doi: https://doi.org/10.1016/j.brs.2021.04.024

Yadav, A.P., Li, D., Nicolelis, M.A.L. (2020), A brain to spine interface for transferring articial sensory information. Scientific Reports, 10, 900, doi: https://doi.org/10.1038/s41598-020-57617-3

Yadav, A.P. and Nicolelis, M. A. L. (2017), Electrical stimulation of the dorsal columns of the spinal cord for Parkinson's disease. Movement Disorders, 32: 820-832, doi: https://doi.org/10.1002/mds.27033

 

Titles & Appointments

  • Assistant Professor of Neurological Surgery
  • Education
    2015 PhD Duke University
    2010 MS Duke University
    2008 BE University of Mumbai
  • Research

    The brain and the spinal cord constitute a sensorimotor system. Injuries or neurological disorders of the nervous system disrupt this closed-loop sensorimotor system. The Yadav lab develops novel neuroengineering technologies such as brain-spine-machine interfaces and closed-loop neuromodulation techniques to restore the disrupted brain-spine connection. We use electrophysiological recordings from multiple brain areas, electrical stimulation of the spinal cord, and machine learning-based algorithms to develop therapeutic applications to treat neurological disorders. We test our methods in rodent models and in collaboration with neurosurgeons and clinicians conduct pilot studies in human subjects. Our goal is to achieve clinical translation of lab-based neural engineering technologies and provide therapeutic solutions to patients affected by Parkinson's disease, spinal cord injury, amputation, stroke, and other neurological disorders.

    To learn more visit: https://yadavlabs.com/

    Interests: brain-spine-machine interfaces, neuroprosthetics, spinal cord stimulation, deep brain stimulation, closed-loop control, Parkinson's disease, spinal cord injury

     

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