51958-Denlinger, Chad

Chad E. Denlinger, MD

Professor of Surgery

EH 202
Indianapolis, IN


Dr. Denlinger joined the IU School of Medicine as a Professor of Surgery in 2020 after practicing thoracic surgery for eleven years in South Carolina. He grew up in Ohio and graduated from the Ohio State School of Medicine in 2000. He then completed his general surgical residency at the University of Virginia and thoracic surgical fellowship at Washington University. His clinical interests are in minimally invasive surgical techniques for the treatment of lung cancer, esophageal cancer, and benign esophageal diseases such as hiatal hernias and esophageal dysmotility. Dr. Denlinger also has an interest in chest wall tumors and advanced lung diseases requiring lung transplantation. His research interests relate to molecular mechanisms of lung cancer’s resistance to chemotherapy and molecularly targeted agents.

Medical School: Ohio State School of Medicine (1996 – 2000)
General Surgery Residency: University of Virginia (2000 - 2007)
Research Fellowship: University of Virginia (2002-2004)
Cardiothoracic Surgery Fellowship: Washington University (2007 - 2009)

Key Publications

Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non-small cell lung cancer. Dimou A, Nasarre C, Peterson YK, Pagano R, Gooz M, Nasarre P, Drabkin HA, Armeson KE, Gibney BC, Gemmill RM, Denlinger CE.J Thorac Cardiovasc Surg. 2020 Online ahead of print


IL-2 and Beyond in Cancer Immunotherapy. Wrangle JM, Patterson A, Johnson CB, Neitzke DJ, Mehrotra S, Denlinger CE, Paulos CM, Li Z, Cole DJ, Rubinstein MP. J Interferon Cytokine Res. 2018;38:45-68


Alternatives to Lobectomy for High-Risk Patients With Early-Stage Non-Small Cell Lung Cancer. Klapper JA, Hittinger SA, Denlinger CE.Ann Thorac Surg. 2017;103:1330-1339


Utility of restaging endoscopic ultrasound after neoadjuvant therapy for esophageal cancer. Griffin JM, Reed CE, Denlinger CE.Ann Thorac Surg. 2012;93:1855-9


Titles & Appointments

  • Professor of Surgery
  • Education
    2020 MD The Ohio State University
    1996 BA Eastern Mennonite University

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