Michael T. Eadon, MD
Assistant Professor of Medicine
Research II, Suite 202D 950 W Walnut St
Indianapolis, IN 46202-5188
Titles & Appointments
- Assistant Professor of Clinical Medicine
- Assistant Research Professor
My primary research efforts focus on the translation and implementation of pharmacogenomics into clinical practice as well as the identification of novel predictors of renal injury from large genomic, transcriptomic, and proteomic datasets. Major focus areas include the evaluation of renal disease expression patterns and identifying genetic variants that affect this expression (expression quantitative trait loci). A second focus is translating genetic determinants of anti-hypertensive drug response and progression of kidney disease into clinical practice.
RegSNPs-intron: a computational framework for predicting pathogenic impact of intronic single nucleotide variants.
Increasing Nephrologist Awareness of Symptom Burden in Older Hospitalized End-Stage Renal Disease Patients.
Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy.
Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial.
Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes.
Quantitative Large-Scale Three-Dimensional Imaging of Human Kidney Biopsies: A Bridge to Precision Medicine in Kidney Disease.
Pharmacogenomic studies of hypertension: paving the way for personalized antihypertensive treatment.
Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach.
Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial.
Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications.
Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes.
TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis.
Whole blood viscosity: Effect of hemodialysis treatment and implications for access patency and vascular disease.
Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion.
American Board of Internal Medicine - Nephrology