4932-DeWitt, John

John M. DeWitt, MD

Professor of Medicine

550 North University Blvd
Suite 4100
UH 4100
Indianapolis, IN 46202-5250
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Dr. DeWitt completed his undergraduate degree at the University of Virginia and medical degree (M.D.) at the Medical College of Virginia (MCV). His internship at the University of North Carolina at Chapel Hill was followed by residency in Internal Medicine and fellowship in Gastroenterology at MCV.  He completed training in advanced endoscopy at the University of Massachusetts.

Dr. DeWitt has been at Indiana University Health since 2001 where he is currently Professor of Medicine and Director of Endoscopic Ultrasound.  He has achieved national and international recognition for research in diagnostic and therapeutic endoscopic ultrasound and pioneered the use of endoscopy for the nonoperative ablation of pancreatic cystic neoplasms. In 2011, he started the submucosal endoscopy program at IU where he performed the first peroral endsocopic myotomy (POEM) for achalasia, first endoscopic submucosal dissection (ESD) for superficial tumors and the first flexible endoscopic treatment for Zenker's diverticulum in Indiana.  He has been active in multiple national societies including past chair of both the Standards of Practice Committee and Publications Committee for the American Society of Gastrointestinal Endoscopy (ASGE) and past chair of the Imaging and Advanced Technology Section of the AGA Council.  He has published over 200 peer-reviewed papers and 200 abstracts on the diagnosis and treatment of gastrointestinal disease. 

Key Publications


1. DeWitt J, Devereaux B, Chriswell M, et al. Comparison of Endoscopic Ultrasound and Multidetector Computed Tomography for the Detection and Staging of Pancreatic Cancer. Ann Int Med 2004; 141:753-763.

2. DeWitt J, Devereaux BM, Lehman GA, et al.  Comparison of Endoscopic Ultrasound and Computed Tomography for the Preoperative Evaluation of Pancreatic Cancer:  A Systematic Review.  Clin Gastroenterol Hepatol 2006; 4:717-725.

3. DeWitt J, McGreevy K, Schmidt CM, et al Endoscopic Ultrasound-Guided Ethanol versus Saline Lavage for Pancreatic Cysts: A Randomized Double Blinded Study. Gastrointest Endosc 2009;70:710-723.

4. DeWitt JM, Sandrasegaran K, Perkins S, et al S.  Phase I study of EUS-guided Photodynamic Therapy for Locally Advanced Pancreatic Cancer.  Gastrointest Endosc 2019; 89:390-398

DeWitt JM, Arain M, Chang KJ, Sharaiha R, Komanduri S, Muthusamy VR, Hwang JH; AGA Center for GI Innovation and Technology. Interventional Endoscopic Ultrasound: Current Status and Future Directions. Clin Gastroenterol Hepatol. 2021 Jan;19(1):24-40.  

6. DeWitt JM, Kessler WR, Wo JM, et al. Symptom Association for Gastroesophageal Reflux Disease by pH Monitoring After Peroral Endoscopic Myotomy. Am J Gastroenterol. 2022 Aug 1;117(8):1316-1319.

Titles & Appointments

  • Professor of Medicine

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