Faculty

Sarath C. Janga, PhD

Chair, Biohealth Informatics School of Informatics & Computing

Phone (317) 278-4147

Address

IT 479
BHI
IN
Indianapolis, IN

Titles & Appointments

Chair, Biohealth Informatics School of Informatics & Computing
Director, Bioinformatics Program and Biomedical Informatics Program, School of Informatics & Computing
Associate Professor of Bioinformatics, School of Informatics & Computing
Adjunct Associate Professor of Medical & Molecular Genetics
Adjunct Associate Professor of Medicine

Education

2010 PhD University of Cambridge

2003 BTECH Indian Institute of Technology

2003 MTECH Indian Institute of Technology
Publications

Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations.
Srivastava R; Budak G; Dash S; Lachke SA; Janga SC; Scientific reports 2017 Sep 14

Mutational landscape of RNA-binding proteins in human cancers.
Neelamraju Y; Gonzalez-Perez A; Bhat-Nakshatri P; Nakshatri H; Janga SC; RNA biology 2017 Oct 12

PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes.
Singh DK; Gholamalamdari O; Jadaliha M; Ling Li X; Lin YC; Zhang Y; Guang S; Hashemikhabir S; Tiwari S; Zhu YJ; Khan A; Thomas A; Chakraborty A; Macias V; Balla AK; Bhargava R; Janga SC; Ma J; Prasanth SG; Lal A; Prasanth KV; Carcinogenesis 2017 Oct 1

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.
Olson MR; Ulrich BJ; Hummel SA; Khan I; Meuris B; Cherukuri Y; Dent AL; Janga SC; Kaplan MH; Journal of immunology (Baltimore, Md. : 1950) 2017 May 3

Seten: a tool for systematic identification and comparison of processes, phenotypes, and diseases associated with RNA-binding proteins from condition-specific CLIP-seq profiles.
Budak G; Srivastava R; Janga SC; RNA (New York, N.Y.) 2017 Mar 23

Community-acquired rhinovirus infection is associated with changes in the airway microbiome.
Kloepfer KM; Sarsani VK; Poroyko V; Lee WM; Pappas TE; Kang T; Grindle KA; Bochkov YA; Janga SC; Lemanske RF Jr; Gern JE; The Journal of allergy and clinical immunology 2017 Mar 19

RNA Editing in Pathogenesis of Cancer.
Baysal BE; Sharma S; Hashemikhabir S; Janga SC; Cancer research 2017 Jun 30

Differential Expression of miRNAs in Nontumor Liver Tissue of Patients With Hepatocellular Cancer Caused by Nonalcoholic Steatohepatitis Cirrhosis.
Liang T; Chalasani NP; Williams KE; Sarasani V; Janga SC; Vuppalanchi R; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2016 Oct 22

Dissecting the expression relationships between RNA-binding proteins and their cognate targets in eukaryotic post-transcriptional regulatory networks.
Nishtala S; Neelamraju Y; Janga SC; Scientific reports 2016 May 10

RNA-binding proteins in eye development and disease: implication of conserved RNA granule components.
Dash S; Siddam AD; Barnum CE; Janga SC; Lachke SA; Wiley interdisciplinary reviews. RNA 2016 May 1

Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach.
Srivastava R; Zhang Y; Xiong X; Zhang X; Pan X; Dong XC; Liangpunsakul S; Janga SC; PloS one 2016 Jul 28

Comparative and temporal transcriptome analysis of peste des petits ruminants virus infected goat peripheral blood mononuclear cells.
Manjunath S; Mishra BP; Mishra B; Sahoo AP; Tiwari AK; Rajak KK; Muthuchelvan D; Saxena S; Santra L; Sahu AR; Wani SA; Singh RP; Singh YP; Pandey A; Kanchan S; Singh RK; Kumar GR; Janga SC; Virus research 2016 Dec 23

The RavA-ViaA Chaperone-Like System Interacts with and Modulates the Activity of the Fumarate Reductase Respiratory Complex.
Wong KS; Bhandari V; Janga SC; Houry WA; Journal of molecular biology 2016 Dec 12

ExSurv: A Web Resource for Prognostic Analyses of Exons Across Human Cancers Using Clinical Transcriptomes.
Hashemikhabir S; Budak G; Janga SC; Cancer informatics 2016 Aug 7

Benchmarking of de novo assembly algorithms for Nanopore data reveals optimal performance of OLC approaches.
Cherukuri Y; Janga SC; BMC genomics 2016 Aug 22

Building integrated ontological knowledge structures with efficient approximation algorithms.
Xiang Y; Janga SC; BioMed research international 2015 Oct 13

OperomeDB: A Database of Condition-Specific Transcription Units in Prokaryotic Genomes.
Chetal K; Janga SC; BioMed research international 2015 Oct 12

The human RBPome: from genes and proteins to human disease.
Neelamraju Y; Hashemikhabir S; Janga SC; Journal of proteomics 2015 May 14

Prognostic impact of HOTAIR expression is restricted to ER-negative breast cancers.
Gökmen-Polar Y; Vladislav IT; Neelamraju Y; Janga SC; Badve S; Scientific reports 2015 Mar 5

Uncovering RNA binding proteins associated with age and gender during liver maturation.
Chaturvedi P; Neelamraju Y; Arif W; Kalsotra A; Janga SC; Scientific reports 2015 Mar 31

Differential miRNA Expression in Cells and Matrix Vesicles in Vascular Smooth Muscle Cells from Rats with Kidney Disease.
Chaturvedi P; Chen NX; O'Neill K; McClintick JN; Moe SM; Janga SC; PloS one 2015 Jun 26

Database of RNA binding protein expression and disease dynamics (READ DB).
Hashemikhabir S; Neelamraju Y; Janga SC; Database : the journal of biological databases and curation 2015 Jul 25

Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.
Gökmen-Polar Y; Neelamraju Y; Goswami CP; Gu X; Nallamothu G; Janga SC; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2014 Nov 28

An intricate network of conserved DNA upstream motifs and associated transcription factors regulate the expression of uromodulin gene.
Srivastava R; Micanovic R; El-Achkar TM; Janga SC; The Journal of urology 2014 Mar 1

Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosis.
Vuppalanchi R; Liang T; Goswami CP; Nalamasu R; Li L; Jones D; Wei R; Liu W; Sarasani V; Janga SC; Chalasani N; PloS one 2013 Sep 13

Prediction and validation of the unexplored RNA-binding protein atlas of the human proteome.
Zhao H; Yang Y; Janga SC; Kao CC; Zhou Y; Proteins 2013 Nov 22

From specific to global analysis of posttranscriptional regulation in eukaryotes: posttranscriptional regulatory networks.
Janga SC; Briefings in functional genomics 2012 Nov 3

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