44179-Mandal, Rabindra
Faculty

Rabindra Mandal, PhD

Assistant Research Professor of Pediatrics

Address
R4 451A
PIFB
IN
Indianapolis, IN

Bio

Rabindra K. Mandal, PhD, BVSc & AH is an Assistant Research Professor of Pediatrics infectious diseases at the Indiana University School of Medicine in the Ryan White Center for Pediatric Infectious Diseases and Global Health. He completed his Bachelor of Veterinary Science and Animal Husbandry degree from the Institute of Agriculture and Animal Science (IAAS), Tribhuvan University, Nepal in 2010. Dr. Mandal moved to Fayetteville, Arkansas to complete his doctoral degree in Poultry Science focusing on functional genomics of bacteria and animal microbiome in 2016. He completed postdoctoral training on the role of gut microbiome towards the severe malaria in 2021.

Dr. Mandal is interested in how gut microbial metabolites and toxins impact the severity of malaria. His research has identified mice with severe malaria have gut bacteria with the genomic capacity to produce hemolysins and metabolize sphingosine 1-phosphate (S1P) compared to resistant mice. Particularly, he is interested in how hemolysins, S1P, intestinal homeostasis, and RBC are interconnected to impact the severity of malaria.

Key Publications

Mandal, R.K., Denny, J.E., Namazzi, R., Opoka, R.O., Datta, D., John, C.C. and Schmidt, N.W., 2021. Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection. Cell reports, 35(6), p.109094.

Mandal, R.K., Denny, J.E., Waide, M.L., Li, Q., Bhutiani, N., Anderson, C.D., Baby, B.V., Jala, V.R., Egilmez, N.K. and Schmidt, N.W., 2020. Temporospatial shifts within commercial laboratory mouse gut microbiota impact experimental reproducibility. BMC biology, 18(1), pp.1-12.

Mandal, R.K., Crane, R.J., Berkley, J.A., Gumbi, W., Wambua, J., Ngoi, J.M., Ndungu, F.M. and Schmidt, N.W., 2019. Longitudinal analysis of infant stool bacteria communities before and after acute febrile malaria and artemether-lumefantrine treatment. The Journal of infectious diseases, 220(4), pp.687-698.

Mandal, R.K., Jiang, T. and Kwon, Y.M., 2017. Essential genome of Campylobacter jejuni. BMC genomics, 18(1), pp.1-14.

Mandal, R.K. and Kwon, Y.M., 2017. Global screening of Salmonella enterica serovar Typhimurium genes for desiccation survival. Frontiers in microbiology, 8, p.1723.

Mandal, R.K., Jiang, T., Al-Rubaye, A.A., Rhoads, D.D., Wideman, R.F., Zhao, J., Pevzner, I. and Kwon, Y.M., 2016. An investigation into blood microbiota and its potential association with Bacterial Chondronecrosis with Osteomyelitis (BCO) in Broilers. Scientific reports, 6(1), pp.1-11.

Titles & Appointments

  • Assistant Research Professor of Pediatrics
  • Education
    2016 PhD University of Arkansas
    2010 BVSCAH Tribhuvan University

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