Dr. Hamdouchi is an accomplished scientific leader in drug discovery & development with extensive experience in advancing small molecules from target identification to clinical proof of concept. His areas of expertise include medicinal chemistry; oncology, diabetes, neuroscience & anti-infective research; strategic planning from target selection to clinical proof-of-concept; due diligence & external collaborations in the USA, Europe, and Asia; portfolio enablement & prioritization; mentoring & talent development.
Throughout his 23-year career at Eli Lilly & Company, he oversaw large global cross-functional drug discovery and development teams, championed the creation of multiple drug discovery strategies, and contributed to the discovery and development of a dozen clinical candidates – encompassing novel treatments in cancer, diabetes, and infectious and neurodegenerative disease.
Furthermore, he was the scientific leader responsible for Lilly’s external research & development strategy and successfully developed international drug discovery as an effective extension of global Eli Lilly & Company research capabilities. He established and led Lilly's first R&D outsourced team in Asia capable of executing a drug discovery process from target selection through clinical proof-of-concept, delivering four high quality clinical candidates. As a member of multiple R&D reviewer committees at Eli Lilly & Company, he routinely participated in setting a strategic direction for the company along with governance of the discovery and early clinical development pipeline.
After 23+ years of experience, he retired from Eli Lilly & Company at the end of 2017. In 2018, he joined the Indiana University School of Medicine where he is contributing to the advancement of the science of therapeutics discovery and translational medicine through research and educational programs. Part of his efforts is focused on building the underlying drug discovery & development capabilities of Indiana University Melvin and Bren Simon Comprehensive Cancer Center, implementing effective preclinical and clinical strategies, to deliver a robust and diverse portfolio. He works at the interface of academic-industrial partnerships, building relationships, consulting, strategizing, negotiating, mentoring, and creating an effective collaborative research environment that stimulates the design and execution of target selection, lead generation, lead optimization, candidate selection, and phases I and II clinical development.
His strong leadership in the field is reflected in numerous patents, publications, invited lectures, and awards. Dr. Hamdouchi has flexibility in both language (French, English, Spanish, Arabic and German) and culture to operate successfully in several professional contexts related to the pharmaceutical business.