43949-Powell, Nick

Nick Powell, PharmD

Assistant Research Professor of Medicine

R2 402
Indianapolis, IN
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My current appointment in the Division of Clinical Pharmacology is the culmination of over 10 years of research experience in pharmacy practice, academia, and the pharmaceutical industry. My background in insulin manufacturing at Eli Lilly and Company and my training in pharmacogenomics and computational omics-level analyses provide a unique combination of skills that I use to conduct pharmacogenomics research. Pharmacogenomics research is on the precipice of moving from the current paradigm of monogenic predictors to polygenic predictors of drug response and I aim to advance the field to improve our understanding of the inter-individual variability in drug response.

Key Publications

  1. Powell NR, Shugg T, Ly RC, Albany C, Radovich M, Schneider BP, Skaar TC. Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report. Frontiers in Oncology. 2022 January 31; 11. Available from: https://www.frontiersin.org/article/10.3389/fonc.2021.809527 DOI: 10.3389/fonc.2021.809527
  2. Powell NR, Zhao H, Ipe J, Liu Y, Skaar TC. Mapping the miRNA-mRNA Interactome in Human Hepatocytes and Identification of Functional mirSNPs in Pharmacogenes. Clin Pharmacol Ther. 2021 Oct;110(4):1106-1118. PubMed PMID: 34314509.
  3.  For full list: https://orcid.org/0000-0003-4572-0733 

Titles & Appointments

  • Assistant Research Professor of Medicine

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