43095-Ismail, Heba

Heba Ismail, MBBCH, PhD

Assistant Professor of Pediatrics

RI 5960
Indianapolis, IN


Dr. Ismail attended medical school in Cairo, Egypt. She earned her MBBCh (MD) degree with honors from Cairo University, Faculty of Medicine in 1999. She completed her residency and pediatric endocrine training at Cairo University Children’s Hospital. Dr. Ismail later moved to the United States where she completed her US residency training at T.C. Thompson Children’s Hospital in Chattanooga, TN and her pediatric endocrine fellowship training at Seattle Children’s Hospital. Dr. Ismail became the Clinical Director of the Weight Management Program at Children’s Hospital of Pittsburgh in 2014 and the Clinical Director of the Diabetes Program there in 2016. Dr. Ismail joined the faculty at IU School of Medicine in 2018. She is board certified in Pediatrics as well as Pediatric Endocrinology. Dr. Ismail has a primary interest in type 1 diabetes research as well as clinical management of diabetes.

Key Publications

1: Ismail HM, Xu P, Libman IM, Becker DJ, Marks JB, Skyler JS, Palmer JP, Sosenko
JM; Type 1 Diabetes TrialNet Study Group. The shape of the glucose concentration
curve during an oral glucose tolerance test predicts risk for type 1 diabetes.
Diabetologia. 2018 Jan;61(1):84-92. doi: 10.1007/s00125-017-4453-6. Epub 2017 Sep
27. PubMed PMID: 28956083; PubMed Central PMCID: PMC5850999.

2: Sosenko JM, Geyer S, Skyler JS, Rafkin LE, Ismail HM, Libman IM, Liu YF,
DiMeglio LA, Evans-Molina C, Palmer JP. The influence of body mass index and age
on C-peptide at the diagnosis of type 1 diabetes in children who participated in
the diabetes prevention trial-type 1. Pediatr Diabetes. 2018 May;19(3):403-409.
doi: 10.1111/pedi.12609. Epub 2017 Nov 24. PubMed PMID: 29171129; PubMed Central
PMCID: PMC5918232.

3: Horvat CM, Ismail HM, Au AK, Garibaldi L, Siripong N, Kantawala S, Aneja RK,
Hupp DS, Kochanek PM, Clark RS. Presenting predictors and temporal trends of
treatment-related outcomes in diabetic ketoacidosis. Pediatr Diabetes. 2018
Aug;19(5):985-992. doi: 10.1111/pedi.12663. Epub 2018 Apr 26. PubMed PMID:

4: Evans-Molina C, Sims EK, DiMeglio LA, Ismail HM, Steck AK, Palmer JP, Krischer
JP, Geyer S, Xu P, Sosenko JM; Type 1 Diabetes TrialNet Study Group. β Cell
dysfunction exists more than 5 years before type 1 diabetes diagnosis. JCI
Insight. 2018 Aug 9;3(15). pii: 120877. doi: 10.1172/jci.insight.120877.
eCollection 2018 Aug 9. PubMed PMID: 30089716; PubMed Central PMCID: PMC6129118.

5: Arslanian S, El Ghormli L, Young Kim J, Bacha F, Chan C, Ismail HM, Levitt
Katz LE, Levitsky L, Tryggestad JB, White NH; TODAY Study Group. The Shape of the
Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of
Heightened Glycemic Failure Rates and Accelerated Decline in β-Cell Function in
TODAY. Diabetes Care. 2019 Jan;42(1):164-172. doi: 10.2337/dc18-1122. Epub 2018
Nov 19. PubMed PMID: 30455329; PubMed Central PMCID: PMC6300703.

6: Ismail HM, Evans-Molina C, DiMeglio LA, Becker DJ, Libman I, Sims EK, Boulware
D, Herold KC, Rafkin L, Skyler J, Cleves MA, Palmer J, Sosenko JM; Type 1
Diabetes Trial Net and Diabetes Prevention Trial-Type-1 (DPT-1) Study Groups.
Associations of HbA1c with the timing of C-peptide responses during the oral
glucose tolerance test at the diagnosis of type 1 diabetes. Pediatr Diabetes.
2019 Jun;20(4):408-413. doi: 10.1111/pedi.12845. Epub 2019 Apr 15. PubMed PMID:

7: Chiang JL, Kirkman MS, Laffel LM, Peters AL; Type 1 Diabetes Sourcebook
Authors. Type 1 diabetes through the life span: a position statement of the
American Diabetes Association. Diabetes Care. 2014 Jul;37(7):2034-54. doi:
10.2337/dc14-1140. PubMed PMID: 24935775; PubMed Central PMCID: PMC5865481.

8: Ismail HM, Rincon M. X-linked adrenal hypoplasia congenita: a case report and
ethical dilemma. Endocr Pract. 2014 Jul;20(7):e126-9. doi: 10.4158/EP14033.CR.
PubMed PMID: 24641931.

9: Ismail H, Ness K. Evaluation of short stature in children. Pediatr Ann. 2013
Nov;42(11):217-22. doi: 10.3928/00904481-20131022-08. Review. PubMed PMID:

10: Ismail HM, White KS, Krischer JP, Chase HP, Cuthbertson D, Palmer JP; DPT-1
Study Group. First test effect in intravenous glucose tolerance testing. Pediatr
Diabetes. 2015 Mar;16(2):129-37. doi: 10.1111/pedi.12064. Epub 2013 Aug 15.
PubMed PMID: 23944770; PubMed Central PMCID: PMC3838455.

11: Ismail H. Self-rated health and factors influencing responses among young
Egyptian type 1 diabetes patients. BMC Public Health. 2011 Apr 7;11:216. doi:
10.1186/1471-2458-11-216. PubMed PMID: 21473776; PubMed Central PMCID:

12: Brooks-Worrell BM, Reichow JL, Goel A, Ismail H, Palmer JP. Identification of
autoantibody-negative autoimmune type 2 diabetic patients. Diabetes Care. 2011
Jan;34(1):168-73. doi: 10.2337/dc10-0579. Epub 2010 Sep 20. PubMed PMID:
20855551; PubMed Central PMCID: PMC3004952.

13: Ismail H. Glycogen storage disease type III presenting with secondary
diabetes and managed with insulin: a case report. Cases J. 2009 Jun 17;2:6891.
doi: 10.4076/1757-1627-2-6891. PubMed PMID: 19829878; PubMed Central PMCID:

Titles & Appointments

  • Assistant Professor of Pediatrics
  • Education
    2014 FEL Pediatric Endocrinology Fellowship, University of Washington
    2011 RES Pediatric Residency, University of Tennessee
    2007 PhD Cairo University
    2006 FEL Pediatric Endocrinology Fellowship, University of Cairo
    2004 RES Pediatric Residency, University of Cairo
    2003 MSC Cairo University
    1999 MBBCH Cairo University
  • Professional Organizations
    American Diabetes Association
    Endocrine Society
    Pediatric Endocrine Society
    Society for Pediatric Research
  • Board Certifications
    American Board of Pediatrics - Pediatrics
    American Board of Pediatrics - Pediatric Endocrinology
  • Awards
    Desc: Trustee Teaching Award
    Scope: University
    Date: 2023-05-01

Looking for patient care?

To schedule an appointment with a faculty member physician of IU School of Medicine, contact Indiana University Health at 888-484-3258 or use the physician finder by clicking the button below.

Find a doctor