Subhadip Ghatak, PhD is an Assistant Professor at the Indiana Center for Regenerative Medicine and Engineering, Indiana University. He did his PhD from West Bengal University of Health Sciences, India on the mechanisms of liver injury and repair in xenobiotic induced toxicity. In 2011, he joined The Ohio State University, Columbus as a post-doctoral researcher. During his post-doctoral work, he studied the mechanism of tissue plasticity and the role of microRNA that contributes to regenerative healing in adults. He was actively involved in the development of a novel non-invasive non-viral tissue nanotransfection platform that can reprogram skin fibroblasts to functional neural and endothelial-like cells. Dr. Ghatak has published in several first-tier peer-reviewed journals such as Nature Nanotechnology, Nanomedicine, Nature communications etc.
His current research interest is on the application of nanotechnology in regenerative medicine. Of all the clinically relevant nanoparticles, lipid nanoparticles are most widely used in translational research and are an excellent tool to deliver therapeutics that are critical for tissue regeneration. He developed novel nanoparticles formulation using FDA approved materials that can effectively deliver oligonucleotides at the site of injury, even to specific cell type. In addition to all these synthetic lipid nanoparticles, his research also involves in the application of extracellular vehicles (EVs), especially the exosome as a natural delivery vehicle capable of enhancing tissue regeneration. Natural tissue developmental processes can be harnessed from a proper understanding of the complexity of these extracellular vesicles to facilitate tissue regeneration that could represent an exciting new phase in medicine.