Wenting Wu, PhD

Bio

Dr.Wu obtained her PhD from Fudan University and subsequently completed postdoctoral training in human genetics, genetic epidemiology and bioinformatics at University of California, San Diego and Indiana University.  Dr.Wu is utilizing integrative approach, combining computational, comparative, and functional genomic methods to investigate the genomics and transcription regulation of complex disease mechanism and personalizing medicine. She has published 70 original research articles in peer-reviewed journals, with a total of > 3,809 citations (Google scholar, H-index = 28).

Key Publications

Full list of publications can be accessed at Google Scholar https://scholar.google.com/citations?hl=en&user=1dF9-s0AAAAJ&view_op=list_works&sortby=pubdate

Selected publications

1. Wu W, Syed F, Simpson E, Lee C, Liu J, Chang G, Dong C, Seitz C, L. Eizirik D, G. Mirmira R, Liu Y, Evans-Molina C: The Impact of Pro-Inflammatory Cytokines on Alternative Splicing Patterns in Human Islets. Diabetes 2021;71:116-127.(Cover Image)
2. Kusmartseva I*, Wu W*, Syed F*, Van Der Heide V*, Jorgensen M*, Joseph P, Tang X, Candelario-Jalil E, Yang C, Nick H, et al. Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19. Cell Metabolism 2020, 32 (6) :1041-1051.e6 (Co-first author).
3. Anderson-Baucum E, Piñeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RG. Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype. Cell Metabolism. 2021 Sep 7;33(9):1883-1893.
4. Piñeros AR, Gao H, Wu W, Liu Y, Tersey SA, Mirmira RG: Single-Cell Transcriptional Profiling of Mouse Islets Following Short-Term Obesogenic Dietary Intervention. Metabolites 2020;10:513
5. Visconti A, Duffy D, Liu F, Zhu G, Wu W, Cheng Y, Hysi P, Zeng C, Sanna M, Iles M, et al. Genome-wide association study in 176,678 Europeans reveals new genetic loci for tanning response to sun exposure. Nature Communications 2018, 9(1):1684.
6. Zhang T, Choi J, Kovacs MA, Shi J, Xu M, NISC Comparative Sequencing Program, …, Wu W, et al. Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes. Genome Research2018,11: 1621-1635.
7. Marshall C, Howrigan D, Merico D, Thiruvahindrapuram B, Wu W† (5th out of 268 coauthors), Scherer S, Neale B, Sebat J, on behalf of the Schizophrenia and CNV analysis groups of the Psychiatric Genomics Consortium: Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics 2017, 49, 27–35. († One of the lead authors).
8. Chahal HS*, Wu W*, Ransohoff KJ, Yang L, Hedlin H, Desai M, Lin Y, Dai H-J, Qureshi AA, Li W-Q et al: Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.  Nature Communications2016, 7:12510. (Co-first author).
9. Wu W, Wagner EK, Hao Y, Rao X, Dai H, Han J, Chen J, Storniolo AMV, Liu Y, He C: Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer. Scientific Reports2016, 6:32731.
10. Michaelson JJ, Shi Y, Gujral M, Zheng H, Malhotra D, Jin X, Jian M, Liu G, Greer D, Bhandari A, Wu W, et al: Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation. Cell, 2012, 151(7): 1431-1442.
11. Wang H*, Wu W*, Wang H, Wang S, Chen Y, Zhang X, Yang J, Zhao S, Ding H, Lu D: Analysis of specialized DNA polymerases expression in human gliomas: association with prognostic significance. Neuro-Oncology2010, 12(7): 679-686. (Co-first author).
12. Wu W, Zhang W, Qiao R, Chen D, Wang H, Wang Y, Zhang S, Gao G, Gu A, Shen J et al: Association of XPD Polymorphisms with Severe Toxicity in Non-Small Cell Lung Cancer Patients in a Chinese Population. Clinical Cancer Research, 2009, 15(11): 3889-3895.