38872-Pilbeam, Kristy
Faculty

Kristy Pilbeam

Assistant Professor of Clinical Pediatrics

Address
705 Riley Hospital Drive
ROC 4340

Indianapolis, IN 46202

Bio

Dr. Pilbeam grew up in Grand Rapids, Michigan and went to the University of Pittsburgh where she got a BA in political science and cultural studies. She spent 2 years doing immunology research at the University of Pittsburgh Starlz Transplant Institute before attending the Lake Erie College of Osteopathic Medicine in Erie, PA. After completing her medical degree she went to Advocate Christ Children’s Hospital in Chicago, IL for her Pediatric Residency. In 2017 she completed her fellowship in Pediatric Hematology Oncology at the University of Minnesota. Her research during fellowship focused on new targeted therapies for pediatric sarcoma. She accepted a position at the Indiana University School of Medicine, Riley Hospital for Children in 2017 where she will continue to work on new therapies for pediatric sarcoma and care for patients with both oncologic and hematologic disorders.

Key Publications

Sept 2017: Kristy Pilbeam1, Hongbo Wang1, Elizabeth Taras2, Daniel A. Vallera2,* Michael R. Verneris, et al. Targeting Pediatric Sarcoma with a bispecific immunotoxin targeting urokinase and Epidermal Growth Factor Receptors. Oncotarget. https://doi.org/10.18632/oncotarget.21187

Feb 2017: Antonella Borgatti1,2,3, Kristy Pilbeam14, Jaime Modiano, Daniel Vallera, et al. “Safe and effective sarcoma therapy through bispecific targeting of EGFR and uPAR” Molecular Cancer Therapeutics.

Oct  2016 Pilbeam K, Lund T. Pediatric Multiple Myeloma. Blood: Section- Medical Images                                   

2008: Pilbeam K, and L Borghesi “The Ontogeny and fate of NK cells marked by Permanent DNA rearrangements”J.Immunol.2008 180:1432-1441

2007 Pilbeam K, N Vujanovic and L Borghesi “Ontogeny of natural killer cells in man and mouse” Chapter One: Everything You Always Wanted to Know About NK Cells But Were Afraid to Ask?

Titles & Appointments

  • Assistant Professor of Clinical Pediatrics
  • Research

    Dr. Pilbeam recently completed her fellowship research which was focused on new targeted therapies for pediatric sarcoma. She worked with a bispecific ligand toxin that was targeted to EGFR and uPAR, receptors expressed on sarcoma cells. Through in vivo and in vitro evaluation her work found that this bispecific ligand toxin could successfully target and kill sarcoma cells and bulky tumors. Her work was funded by the Children’s Cancer Research fund at the University of Minnesota and the Hyundai Hope on Wheels grant.

  • Professional Organizations
    American Association for Cancer Research
    American Society for Pediatric Hematology/Oncology
    American Society of Hematology
  • Board Certifications
    American Board of Pediatrics - Pediatrics
  • Clinical Interests

    Pediatric Hematology and Oncology with a focus on Sarcomas and Hepatic Tumors. Translational medicine focusing on clinical trial development for new cancer therapeutic agents.

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