Kenneth P. Nephew, PhD
Professor of Cellular & Integrative Physiology, Medical Sciences Program
1983, BS The Ohio State University (Animal Sciences)
1986, MS The Ohio State University (Dairy Science; Reproductive Physiology)
Effect of Prostaglandin F2 alpha on Lipoprotein Utilization in Cultured Bovine Luteal Cells
1991, PhD The Ohio State University (Animal Sciences; Reproductive Physiology)
Role of Embryonic Migration and Trophoblast Interferons on Maternal Recognition of Pregnancy
1991-1992 Postdoctoral Fellow, Department of Obstetrics and Gynecology University of Kansas School of Medicine (Center for Reproductive Medicine, Wichita)
1992-1996 NIH Postdoctoral Fellow, Department of Cancer Biology University of Cincinnati, College of Medicine
1996-2002 Assistant Professor of Cellular and Integrative Physiology Indiana University School of Medicine
2002-2006 Associate Professor of Cellular and Integrative Physiology (tenure) Indiana University School of Medicine
2007-Present Professor of Cellular and Integrative Physiology
Adjunct Professor of Molecular and Cellular Biochemistry
Adjunct Professor of Obstetrics and Gynecology Indiana University School of Medicine
Titles & Appointments
- Adjunct Professor of Obstetrics & Gynecology, Medical Sciences Program
- Fellow, Indiana Molecular Biology Institute, College of Arts and Sciences, IU Bloomington
- Adjunct Professor of Biology, College of Arts & Sciences, IU Bloomington
MAJOR RESEARCH INTERESTS
Women’s Cancers & Translational Research
Cancer Epigenetics (DNA methylation, histone modifications, non-coding RNAs)
Cancer Stem Cells
Nuclear receptors/steroid hormone action/hormone-associated cancers
Drug resistance (ovarian and breast cancers)
BioVLAB-mCpG-SNP-EXPRESS: A system for multi-level and multi-perspective analysis and exploration of DNA methylation, sequence variation (SNPs), and gene expression from multi-omics data.
NF-?B-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer.
Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease.
Regulation of triple-negative breast cancer cell metastasis by the tumor-suppressor liver kinase B1.
Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study.
American Association for the Advancement of Science