26533-Walczak, Claire
Faculty

Claire E. Walczak, PhD

Assistant Director of Research

Phone 8128555919
Address
Myers Hall 262
MSCI
BL
Bloomington, IN 47405
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Bio

Claire E. Walczak, PhD, has been honored with a Leukemia/Lymphoma Society Scholar Award and an American Cancer Society Research Scholar Award as well as a Women in Cell Biology Junior Career Award from the American Society for Cell Biology. She served as a Council Member for the American Society for Cell Biology from 2014-2016. She was chosen as an Exemplar for Research in 2017 and was elected as a fellow of the American Society for Cell Biology and the American Association for Advancement of Science in 2018.

Titles & Appointments

  • Assistant Director of Research
  • Professor of Biochemistry & Molecular Biology
  • Adjunct Professor of Anatomy, Cell Biology & Physiology
  • Adjunct Professor of Biology, College of Arts & Sciences
  • Education
    1993 PhD University of Wisconsin
    1987 BS Rensselaer Polytechnic Institute
  • Research

    The Walczak Lab studies the fundamental mechanisms that cells use to accurately distribute their genetic material to the two daughter cells. Defects in this process lead to aneuploidy and genomic instability, which are hallmarks of cancer. We use a combination of approaches, including high-resolution imaging, biochemistry, genomics and cell/molecular biology to ask fundamental questions about how cells maintain mitotic fidelity and how cell maintain proper ploidy using both normal and tumor cell models. In addition, we are evaluating molecular targets that may be novel biomarkers for cancer progression and that may serve as new therapeutic targets.

     Lab Website: http://walczaklab-iu.strikingly.com/

    CMCB Graduate Program: https://cmcbgraduate.medicine.iu.edu/

  • Publications
    The far C-terminus of MCAK regulates its conformation and spindle pole focusing.
    Zong H; Carnes SK; Moe C; Walczak CE; Ems-McClung SC; Molecular biology of the cell 2016 Mar 3
    Transient Endoreplication Down-Regulates the Kinesin-14 HSET and Contributes to Genomic Instability.
    Chen S; Stout JR; Dharmaiah S; Yde S; Calvi BR; Walczak CE; Molecular biology of the cell 2016 Aug 3
  • Professional Organizations
    American Association for the Advancement of Science
    American Society for Cell Biology
  • Awards
    Org: American Association for the Advancement of Science
    Desc: AAAS Fellow
    Scope: National
    Date: 2018-11-01
    Org: American Society for Cell Biology
    Desc: ASCB Fellow
    Scope: International
    Date: 2018-09-01
    Org: Indiana University School of Medicine
    Desc: Outstanding Faculty Mentor Award
    Scope: University
    Date: 2018-09-01
    Org: American Cancer Society Research Scholar Award
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    Org: Leukemia/Lymphoma Society Scholar
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    Org: Women in Cell Biology Junior Career Award
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    Org: Elected to ASCB Council
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    Org: Nominated for NIGMS Council
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    Org: Exemplar for Research
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