23617-Kim, Jaeyeon

Jaeyeon Kim, DVM, PhD

Associate Professor of Biochemistry & Molecular Biology

(317) 278-9740
980 W. Walnut Street
Walther Hall, Room R3 C252
Indianapolis, IN 46202
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Dr. Kim received a PhD from the University of Illinois at Urbana-Champaign with a study elucidating the molecular mechanism of ovulation regulated by the hormone progesterone and its progesterone receptor. After studying the normal physiology of the ovary for his PhD, his focus shifted to the most devastating pathology of ovary—ovarian cancer. During his postdoctoral training at Baylor College of Medicine, he developed and characterized genetically engineered mouse models of ovarian cancer, which faithfully reproduce the clinical metastases of human ovarian cancer. Since 2015, Dr. Kim has been an Assistant Professor in the Department of Biochemistry and Molecular Biology at the Indiana University School of Medicine, and also an investigator at Indiana University Simon Cancer Center. Harnessing these mouse models, combined with molecular and genetic approaches, his lab focuses on uncovering the molecular etiology and mechanism of ovarian cancer: how it initiates, progresses, and metastasizes, escalating to an incurable malignancy. Among the prime interests is to define the molecular basis underlying the interactions between genes and hormone in the development, progression, and metastasis of ovarian cancer. His research also aims to understand the role of epigenetic changes in the progression of ovarian cancer. Besides, applying insights from these mouse models, his lab also investigates the molecular mechanism of triple-negative breast cancer. A lucid understanding of the molecular underpinning of ovarian and breast cancer will be crucial to medical advances in the early detection, effective treatment of advanced cancer, and prevention of these malignances.

Key Publications

For a complete list of publications, visit PubMed

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