23580-Conroy, Andrea
Faculty

Andrea Conroy, PHD

Assistant Professor of Pediatrics

Bio

Dr. Conroy's research centers on understanding the impact of infections on global women’s and children’s health. Her goal is to develop new tools to identify patients at risk of adverse clinical outcomes who may benefit from targeted therapies. She received her training at the University of Toronto in a translational global health research environment focusing on malaria pathogenesis and the development of new therapeutics for severe malaria.

Dr. Conroy has two main areas of focus. First, she is interested in understanding how malaria in pregnancy alters the expression of proteins important for regulating placental blood vessel development and fetal growth. She is evaluating a novel point-of-care test to identify women at risk of adverse pregnancy outcomes that may benefit from interventions to improve placental vascular development and fetal growth. Second, she is evaluating the long term implications of acute kidney injury on clinical recovery from severe malaria. Dr. Conroy has extensive experience conducting global health research in the field having spent over five years living and working in East Africa. She has conducted research studies on malaria and HIV in pregnant women and children in East Africa (Kenya, Uganda, Malawi), dengue and leptospirosis in Colombia, and sepsis and influenza in North America. 

Key Publications

Conroy AL, McDonald CR, Gamble JL, Olwoch P, Natureeba P, Cohan D, Kamya MR, Havlir DV, Dorsey G, Kain KC. Altered angiogenesis as a common mechanism underlying preterm birth, small-for-gestational age and stillbirth in women living with HIV. AJOG. 2017. Oct. 11, epub.

Conroy AL, Hawkes M, Morgan C, Elphinstone RE, Barker K, Namasopo S, John CC, Liles WC, Opoka RO, Kain KC. Acute kidney injury is common in pediatric severe malaria and associated with increased mortality. OFID. 2016 Feb. 26;3(2):ofw046.

Conroy AL, Hawkes M, Namasopo S, John CC, Liles WC, Opoka RO, Kain KC. Prospective validation of pediatric disease severity scores to predict in-hospital mortality in Ugandan children with malaria and non-malaria febrile illness. Crit Care. 2015 Feb 15, 19:47.

Conroy AL, Silver KL, Zhong K, Rennie M, Ward P, Sarma JV, Molyneux ME, Sled J, Fletcher JF, Rogerson SJ,  Kain KC. Complement Activation and the Resulting Placental Insufficiency Drives Fetal Growth Restriction Associated with Placental Malaria. Cell Host Microbe. 2013 Feb;13(2):215-226. 

Titles & Appointments

  • Assistant Professor of Pediatrics
  • Education
    2015 FEL University of Toronto
    2011 PHD University of Toronto
    2006 HBSC University of Guelph
  • Research

    Pathogenesis of malaria in pregnancy and childhood; identifying and validating biomarkers to risk stratify patients (e.g. children at increased risk of death/neurologic impairment); the epidemiology of severe malaria; and evaluating new adjunctive therapies for malaria.

  • Professional Organizations
    American Society of Tropical Medicine and Hygiene
    International Society for Infectious Diseases
  • Awards
    Org: Canadian Institutes of Health Research
    Desc: Post-PhD Fellowship
    Scope: International
    Date:
    Org: Society for Gynecologic Investigation
    Desc: Outstanding Research by a Junior Investigator in Fetal Medicine and Placental Function
    Scope: International
    Date:
    Org: American Society of Tropical Medicine and Hygiene
    Desc: Young Investigators Award
    Scope: International
    Date:

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