Naikui Liu, MD, PhD, MD, PhD, MSC
Associate Research Professor of Neurological Surgery
Nai-Kui Liu joined the IU Spinal Cord and Brain Injury Research Group as a Research Assistant Professor in the IU School of Medicine Department of Neurological Surgery and Stark Neurosciences Research Institute in September 2007. Dr. Liu has more than 30 years’ experience in medical research and has been working in the field of spinal cord injury for more than 15 years. His research has appeared in more than 60 articles in peer-reviewed journals, including Annals of Neurology, Experimental Neurology, Journal of Neuroscience, Journal of Nature Journal ofNeurotrauma, Glia, Journal of Neuroscience Research, PLoS ONE, Journal of Neuropathology & Experimental Neurology, and Brain Research. An Editorial Comment by Dr. Linda Noble, former president of the Neurotrauma Society in the journal Annals of Neurology (2006) described one of the studies by Liu and colleagues (2006) concerning phospholipase A2(PLA2) as a novel target for therapeutic intervention of spinal cord injury. Dr. Liu’s current research focuses on the molecular mechanisms of spinal cord injury, neuroprotection and recovery of function following injuries to the CNS, particularly to the spinal cord.
List of Published Work in MyBibliography:http://www.ncbi.nlm.nih.gov/sites/myncbi/naikui.liu.1/bibliography/44005199/public/?sort=date&direction=descending
NB 500A, Neuroscience Research Bldg.
Dr. Liu’s research focuses on the molecular mechanisms of spinal cord injury (SCI), neuroprotection and recovery of function following injuries to the central nervous system (CNS). Currently, his research is focused on four separate projects: 1)Investigation into whether phospholipase A2(PLA2) is a therapeutic target for SCI; 2) Exploring the molecular role of anionic phospholipids, particularly mitochondria-specific cardiolipin in the signaling pathway of neuronal death after SCI; 3)Investigating the role of miRNAs in pathogenesis of SCI; and 4), After establishing several well-accepted models of traumatic brain injury (TBI) and developed new TBI models for their own need, these models are used to investigate the role of cPLA2 in TBI, and whether blocking PSD-95 and nNOS interaction results in neuroprotection. The goal is to develop a novel repair strategy to improve anatomical reorganization and functional recovery after traumatic CNS injuries.