17300-Jacob, Seethal

Seethal A. Jacob, MD

Associate Professor of Pediatrics

705 Riley Hospital Drive
ROC 4340
Indianapolis, IN 46202
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Dr. Seethal Jacob is an Assistant Professor of Pediatrics.  She graduated from Wright State Boonshoft School of Medicine in 2009 and completed her pediatric residency and chief residency at Indiana University School of Medicine.  She went on to complete a fellowship in Pediatric Hematology-Oncology, as well as a Masters in Clinical Research at the University of Pittsburgh, where she began researching the genetic association of sickle cell disease and its various complications.  After fellowship, she returned to Indiana University/Riley Hospital for Children as part of the Pediatric and Adolescent Comparative Effectiveness Research (PACER) group and Director of the Comprehensive Pediatric Sickle Cell Program at Riley.  Her research focuses on developing and evaluating interventions, such as telehealth, to improve access to and the quality of care for children living with sickle cell disease.

Key Publications

Jacob SA, Talati R, Kanter J. The evolving treatment landscape for children with sickle cell disease. Lancet Child Adolesc Health. 2023 Nov;7(11):797-808. doi: 10.1016/S2352-4642(23)00201-8. Review. PubMed PMID: 37858508.

Jacob SA, Bouck J, Daas R, Jackson MD, LaMotte JE, Carroll AE. Understanding caregiver burden with accessing sickle cell care in the Midwest and their perspective on telemedicine. BMC Health Serv Res. 2023 May 17;23(1):500. doi: 10.1186/s12913-023-09383-x. PubMed PMID: 37198614; PubMed Central PMCID: PMC10189684.

Jacob SA, Carroll AE, Bennett WE Jr. A feasibility study of telemedicine for paediatric sickle cell patients living in a rural medically underserved area. J Telemed Telecare. 2021 Aug;27(7):431-435. doi: 10.1177/1357633X19883558. Epub 2019 Nov 6. PubMed PMID: 31694482; PubMed Central PMCID: PMC8934441.

Jacob SA, Meier ER. Importance of sickle cell trait counseling for adolescents and young adults.Pediatr Blood Cancer. 2021 Dec;68(12):e29300. doi: 10.1002/pbc.29300. Epub 2021 Aug 16. PubMed PMID: 34399031; PubMed Central PMCID: PMC8965882.

Martin OY, Thompson SM, Carroll AE, Jacob SA. Emergency Department Provider Survey Regarding Acute Sickle Cell Pain Management. J Pediatr Hematol Oncol. 2020 Aug;42(6):375-380. doi: 10.1097/MPH.0000000000001843. PubMed PMID: 32569034; PubMed Central PMCID: PMC9024381.

Jacob SA, Novelli EM, Isenberg JS, Garrett ME, Chu Y, Soldano K, Ataga KI, Telen MJ, Ashley-Koch A, Gladwin MT, et al. Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia. Am J Hematol. 2017 Mar;92(3):E31-E34. doi: 10.1002/ajh.24635



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