16860-Johnson, Philip
Faculty

Philip L. Johnson, PhD

Associate Professor of Anatomy, Cell Biology & Physiology

Address
NB 314F, Neuroscience Research Bldg.

IN
Indianapolis, IN

Bio

 

Academic Appointments

 

2008-2010: Assistant Research Professor, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN

2010-2012: Assistant Professor, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN

2012-Present: Assistant Professor, Department of Anatomy & Cell Biology, Indiana University School of Medicine, Indianapolis, IN

  

Honors

 

2012: Scholars Abstract Award, Clinical and Translational Research and Education Meeting ACRT/SCTS

2011: Poster selected for Data Blitz session 50th Anniversary American College of Neuropsychopharmacology

2010: Scholars Abstract Award, Clinical and Translational Research and Education Meeting ACRT/SCTS

2009: Young Investigator Award, NARSAD

2009: Who's Who in Medicine Education

2007: Junior Faculty Award, Anxiety Disorders Association of America

2007: 1st Place Poster Award: Indianapolis Chapter of Society for Neuroscience Meeting

2005: Organon Prize: Most outstanding article of 2005, J. Psychopharmacology

2003: Brain: Journal of Neurology Travel Award

2002: University of Bristol Alumni Travel Award

2002: Neuroendocrinology Charitable Trust Travel Award

1999: USD Biology Departmental Travel Award

1998: Phi Sigma Honorary Society

Titles & Appointments

  • Associate Professor of Anatomy, Cell Biology & Physiology
  • Education
    2008 FEL Indiana University School of Medicine
    2005 PhD University of Bristol
    2000 MSC University of South Dakota
    1998 BSC University of South Dakota
  • Research

    My overall career goal is to integrate preclinical and clinical research to investigate the mechanisms of centrally regulated anxiety and panic-associated behavior that coincides with cardio-respiratory and thermoregulatory activity, and determine how these systems contribute to menopausal symptoms (e.g., hot flashes and anxiety) from loss of estrogen tone; neuropsychiatric disorders such as panic disorder and post traumatic stress disorder (PTSD); and respiratory disorders such as chronic obstructive pulmonary disorder (COPD).  To accomplish this I employ a variety of techniques such as: development and use of animal models (i.e., “hot flashes”,  panic disorder, PTSD and COPD); site specific brain target and peripheral pharmacological interventions; functional neuroanatomical techniques (tract tracing and ex vivo functional imaging); cell and region specific neuronal lesions, genetically silencing critical proteins using small interfering RNA within these regions [e.g., neuropeptides, receptors, transporters or synthesizing enzymes].  I am also receiving training from and collaborating with Luis DeLecea from Stanford University (whom co-discovered the orexin peptide in 1998) on the use of optogenetics to inhibit or activate specific neurochemical systems in vivo.  These techniques, when utilized collectively, produce a detailed understanding of not only the putative neuronal circuitry involved in the regulation of behavior and associated autonomic and respiratory activity, but also how disruption of this neuronal circuitry lead to aberrant behavior and physiology.  This information then becomes vital to understanding treatment mechanisms and which can then lead to elucidating new and selective targets for acute and potentially long-term treatments of associated disorders and for screening potentially useful pharmacological and even genetic treatments.

  • Professional Organizations
    Anxiety Disorder Association of America
    Associate Member of Faculty of 1000
    International Behavioral Neuroscience Society
    International Brain Research Organization
    New York Academy of Sciences
    Society for Neuroscience

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