Michele T. Yip-Schneider, PhD
Senior Research Professor Emeritus of Surgery
- myipschn@iu.edu
- Phone
- 317-278-4739
- Address
-
Walther Hall (R3), 541C
980 W. Walnut St.
Indianapolis, IN 46202 - PubMed:
Bio
Dr. Yip-Schneider is currently Senior Research Professor of Surgery. She received her PhD in Biochemistry from the University of California, Davis. Following post-doctoral training at the University of California, Los Angeles and Indiana University School of Medicine, she joined the Department of Surgery faculty in 2001.
Dr. Yip-Schneider’s research focus is on pancreatic cancer and pancreatic cysts, some of which have malignant potential. This work encompasses the search for potential targets, therapeutics, and biomarkers for earlier detection and prevention. She has more than 75 peer reviewed publications.
Key Publications
Yip-Schneider MT, Wu H, Dumas RP, Hancock BA, Agaram N, Radovich M, Schmidt CM: Vascular endothelial growth factor, a novel and highly accurate pancreatic fluid biomarker for serous pancreatic cysts. J Am Coll Surg 218(4):608-17, 2014.
Yip-Schneider MT, Carr RA, Wu H, Schmidt CM: Prostaglandin E2: A Pancreatic Fluid Biomarker of IPMN Dysplasia. J Am Coll Surg 225(4):481-487, 2017.
Carr RA, Yip-Schneider MT, Simpson RE, Dolejs S, Schneider JG, Wu H, Ceppa EP, Park W, Schmidt CM: Pancreatic Cyst Fluid Glucose: Rapid, Inexpensive, and Accurate Diagnosis of Mucinous Pancreatic Cysts. Surgery 163(3):600-605, 2018.
Fahrmann JF, Schmidt CM, Mao X, Irajizad E, Loftus M, Zhang J, Patel N, Vykoukal J, Dennison JB, Long JP, Do KA, Zhang J, Chabot JA, Kluger MD, Kastrinos F, Brais L, Babic A, Jajoo K, Lee LS, Clancy TE, Ng K, Bullock A, Genkinger J, Yip-Schneider MT, Maitra A, Wolpin BM, Hanash S: Lead-time trajectory of CA19-9 as an anchor marker for pancreatic cancer early detection. Gastroenterology 160(4):1373-1383, 2021.
Yip-Schneider MT, Wu H, Allison HR, Easler JJ, Sherman S, Al-Haddad MA, Dewitt JM, Schmidt CM: Biomarker Risk Score Algorithm and Preoperative Stratification of Patients with Pancreatic Cystic Lesions. J Am Coll Surg 233(3):426-434, 2021.
Year | Degree | Institution |
---|---|---|
1988 | PhD | University of California, Davis |
1982 | AB | University of California, Berkeley |
Our laboratory currently seeks to identify potential biomarkers that can aid in the differential diagnosis of pancreatic lesions. With the increased frequency of diagnostic imaging, pancreatic cysts are now detected in >2% of the American adult population. Importantly, some cystic lesions of the pancreas have the potential to develop into pancreatic adenocarcinoma and may therefore serve as a clinical window of opportunity. In contrast, others have little or no malignant potential. The discovery of reliable biomarkers will facilitate risk stratification, thus promoting early detection and prevention of pancreatic cancer in high-risk patients while reducing unnecessary major surgery in those at low risk of malignancy.
Ramachandran PV; Helppi MA; Lehmkuhler AL; Marchi JM; Schmidt CM; Yip-Schneider MT; Bioorganic & medicinal chemistry letters 2015 Jul 30
Waters JA; Matos J; Yip-Schneider M; Aguilar-Saavedra JR; Crean CD; Beane JD; Dumas RP; Suvannasankha A; Schmidt CM; Surgery 2015 Jul 21
Springer S; Wang Y; Dal Molin M; Masica DL; Jiao Y; Kinde I; Blackford A; Raman SP; Wolfgang CL; Tomita T; Niknafs N; Douville C; Ptak J; Dobbyn L; Allen PJ; Klimstra DS; Schattner MA; Schmidt CM; Yip-Schneider M; Cummings OW; Brand RE; Zeh HJ; Singhi AD; Scarpa A; Salvia R; Malleo G; Zamboni G; Falconi M; Jang JY; Kim SW; Kwon W; Hong SM; Song KB; Kim SC; Swan N; Murphy J; Geoghegan J; Brugge W; Fernandez-Del Castillo C; Mino-Kenudson M; Schulick R; Edil BH; Adsay V; Paulino J; van Hooft J; Yachida S; Nara S; Hiraoka N; Yamao K; Hijioka S; van der Merwe S; Goggins M; Canto MI; Ahuja N; Hirose K; Makary M; Weiss MJ; Cameron J; Pittman M; Eshleman JR; Diaz LA Jr; Papadopoulos N; Kinzler KW; Karchin R; Hruban RH; Vogelstein B; Lennon AM; Gastroenterology 2015 Aug 4
Yip-Schneider M; Schmidt CM; Journal of the American College of Surgeons 2014 Sep
Ramachandran PV; Nicponski DR; Nair HN; Helppi MA; Gagare PD; Schmidt CM; Yip-Schneider MT; Bioorganic & medicinal chemistry letters 2013 Sep 30
Chan IS; Guy CD; Machado MV; Wank A; Kadiyala V; Michelotti G; Choi S; Swiderska-Syn M; Karaca G; Pereira TA; Yip-Schneider MT; Max Schmidt C; Diehl AM; Alcoholism, clinical and experimental research 2013 Oct 24
Yip-Schneider MT; Wu H; Hruban RH; Lowy AM; Crooks PA; Schmidt CM; Pancreas 2013 Jan
Yip-Schneider MT; Wu H; Dumas RP; Hancock BA; Agaram N; Radovich M; Schmidt CM; Journal of the American College of Surgeons 2013 Dec 24
Yip-Schneider MT; Wu H; Stantz K; Agaram N; Crooks PA; Schmidt CM; BMC cancer 2013 Apr 17
Ramachandran PV; Nicponski DR; Drolet MP; Schmidt CM; Yip-Schneider MT; Future medicinal chemistry 2013 Apr
Holcomb BK; Yip-Schneider MT; Waters JA; Beane JD; Crooks PA; Schmidt CM; Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012 May 23
Doyle CJ; Yancey K; Pitt HA; Wang M; Bemis K; Yip-Schneider MT; Sherman ST; Lillemoe KD; Goggins MD; Schmidt CM; Pancreas 2012 Mar
Doyle CJ; Agaram NP; Yip-Schneider MT; Schmidt CM; Pancreas 2011 Mar
Yip-Schneider MT; Doyle CJ; McKillop IH; Wentz SC; Brandon-Warner E; Matos JM; Sandrasegaran K; Saxena R; Hennig ME; Wu H; Waters JA; Klein PJ; Froehlich JC; Schmidt CM; Alcoholism, clinical and experimental research 2011 Jul 25
Yang Y; Liu H; Li Z; Zhao Z; Yip-Schneider M; Fan Q; Schmidt CM; Chiorean EG; Xie J; Cheng L; Chen JH; Zhang JT; International journal of biochemistry and molecular biology 2011 Jan 1
Ramachandran PV; Pratihar D; Nair HN; Walters M; Smith S; Yip-Schneider MT; Wu H; Schmidt CM; Bioorganic & medicinal chemistry letters 2010 Sep 21
Li Z; Dong Z; Myer D; Yip-Schneider M; Liu J; Cui P; Schmidt CM; Zhang JT; BMC cancer 2010 Nov 1
Hennig M; Yip-Schneider MT; Wentz S; Wu H; Hekmatyar SK; Klein P; Bansal N; Schmidt CM; Hepatology (Baltimore, Md.) 2010 Apr
Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM; The Journal of pharmacology and experimental therapeutics 2009 Mar 3
Ramachandran PV; Yip-Schneider M; Schmidt CM; Future medicinal chemistry 2009 Apr
Yip-Schneider MT; Wu H; Njoku V; Ralstin M; Holcomb B; Crooks PA; Neelakantan S; Sweeney CJ; Schmidt CM; Pancreas 2008 Oct
Wentz SC; Yip-Schneider MT; Gage EA; Saxena R; Badve S; Schmidt CM; The Journal of surgical research 2008 Nov 7
Choi J; Yip-Schneider M; Albertin F; Wiesenauer C; Wang Y; Schmidt CM; The Journal of surgical research 2008 Mar 3
Hennig M; Yip-Schneider MT; Klein P; Wentz S; Matos JM; Doyle C; Choi J; Wu H; O'Mara A; Menze A; Noble S; McKillop IH; Schmidt CM; The Journal of surgical research 2008 Dec 13
Holcomb B; Yip-Schneider M; Schmidt CM; Pancreas 2008 Apr
Wentz SC; Wu H; Yip-Schneider MT; Hennig M; Klein PJ; Sebolt-Leopold J; Schmidt CM; Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2007 Nov 7
Holcomb B; Yip-Schneider MT; Matos JM; Dixon J; Kennard J; Mahomed J; Shanmugam R; Sebolt-Leopold J; Schmidt CM; Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2007 Nov 30
Schmidt CM; Yip-Schneider MT; Ralstin MC; Wentz S; DeWitt J; Sherman S; Howard TJ; McHenry L; Dutkevitch S; Goggins M; Nakeeb A; Lillemoe KD; Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2007 Nov 20
Yip-Schneider MT; Wu H; Ralstin M; Yiannoutsos C; Crooks PA; Neelakantan S; Noble S; Nakshatri H; Sweeney CJ; Schmidt CM; Molecular cancer therapeutics 2007 May 31
Vegeler RC; Yip-Schneider MT; Ralstin M; Wu H; Crooks PA; Neelakantan S; Nakshatri H; Sweeney CJ; Schmidt CM; The Journal of surgical research 2007 Aug 31
Shanmugam R; Jayaprakasan V; Gokmen-Polar Y; Kelich S; Miller KD; Yip-Schneider M; Cheng L; Bhat-Nakshatri P; Sledge GW Jr; Nakshatri H; Zheng QH; Miller MA; DeGrado T; Hutchins GD; Sweeney CJ; The Prostate 2006 Oct 1
Crowell PL; Schmidt CM; Yip-Schneider MT; Savage JJ; Hertzler DA 2nd; Cummings WO; Neoplasia (New York, N.Y.) 2006 Jun
Ralstin MC; Gage EA; Yip-Schneider MT; Klein PJ; Wiebke EA; Schmidt CM; Molecular cancer research : MCR 2006 Jun
Klein PJ; Schmidt CM; Wiesenauer CA; Choi JN; Gage EA; Yip-Schneider MT; Wiebke EA; Wang Y; Omer C; Sebolt-Leopold JS; Neoplasia (New York, N.Y.) 2006 Jan
Yip-Schneider MT; Nakshatri H; Sweeney CJ; Marshall MS; Wiebke EA; Schmidt CM; Molecular cancer therapeutics 2005 Apr
Wiesenauer CA; Yip-Schneider MT; Wang Y; Schmidt CM; Journal of the American College of Surgeons 2004 Mar
Yip-Schneider MT; Schmidt CM; Pancreas 2003 Nov
Sweeney CJ; Marshall MS; Barnard DS; Heilman DK; Billings SD; Cheng L; Marshall SJ; Yip-Schneider MT; Cancer detection and prevention 2002
Yip-Schneider MT; Sweeney CJ; Jung SH; Crowell PL; Marshall MS; The Journal of pharmacology and experimental therapeutics 2001 Sep
Yip-Schneider MT; Lin A; Marshall MS; Biochemical and biophysical research communications 2001 Feb 2
Yip-Schneider MT; Miao W; Lin A; Barnard DS; Tzivion G; Marshall MS; The Biochemical journal 2000 Oct 1
Yip-Schneider MT; Barnard DS; Billings SD; Cheng L; Heilman DK; Lin A; Marshall SJ; Crowell PL; Marshall MS; Sweeney CJ; Carcinogenesis 2000 Feb
Yip-Schneider MT; Lin A; Barnard D; Sweeney CJ; Marshall MS; International journal of oncology 1999 Aug
Yip-Schneider MT; Horie M; Broxmeyer HE; Blood 1995 Jun 15
Broxmeyer HE; Benninger L; Yip-Schneider M; Braun SE; Blood cells 1994
Yip-Schneider MT; Horie M; Broxmeyer HE; Experimental hematology 1993 Dec