14647-Bell, David
Faculty

David R. Bell, PhD, MS

Associate Professor Emeritus of Anatomy, Cell Biology & Physiology

Address
IPFW Med Ed 111
MEDF
FW
Fort Wayne, IN
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Bio

   

Dr. Bell joined the faculty of the Indiana University of Medicine- Fort Wayne in 1989 after serving as a research fellow in the Department of Cardiology at Henry Ford Hospital in Detroit, MI. He is currently a full time, tenured Associate Professor in the Department of Anatomy, Cell Biology and Physiology at the IUSM in Fort Wayne. Dr. Bell received BS magna cum laude and MS in Physiology and Biophysics from Michigan State University and then follow his mentor to join the NIH Specialized Center of Research in Hypertension at the University of Alabama-Birmingham Medical Center where he received his Ph.D. in 1983 in Physiology and Biophysics. He did his post-doctoral research fellowship as an NIH awardee in the Hypertension Program Project in the Department of Physiology at the University of Michigan. Dr. Bell’s research interests have focused on cardiovascular pathophysiology. He has conducted and published his research on functional vascular abnormalities in hypertension, including the pathophysiology related to special circulations, vascular smooth muscle, and the vascular endothelium. He has also published works in cardiac and coronary arterial fluid mechanics. His most recent studies focused on modulation of coronary vascular smooth muscle and endothelial NO function by estrogens and natural polyphenolics. His work also addressed how these compounds protect coronary arteries from oxygen radical mediated injury. He has given numerous presentations and invited seminars on his research at national and international meetings for over 40 years and received a top ten newsworthy designation by the American Physiological Society for his work on plant polyphenolics and vascular function. 

     Prior to the curricular redesign initiative at the IUSM, he served as course director, developer and sole instructor for the Medical Physiology course at the IUSM-Fort Wayne as well as an instructor for several areas of the Medical Pharmacology course where he also served as co-course director. He is the site director for the new Fundamentals of Health and Disease, and Hematology and Cardiology courses at the IUSM-Fort Wayne. He is also a member of the course management team for both courses. Dr. Bell is co-editor and chief author of 4 editions of a major medical physiology textbook, the author of a medical physiology review textbook and a multiple chapter author in an undergraduate physiology textbook. He is currently a member of the live faculty with Kaplan North America where he has responsibility for physiology instruction in the STEP1 prep program. He is the national chairman in physiology for Doody’s Review Services, Inc. where he reviews all new textbooks, specialty texts and research monographs published worldwide to assess their suitability for, and niche within, medical school and hospital libraries. He was a member of the IUSM Admissions Committee for 15 years and is currently a member of the IUSM Curriculum Council Steering Committee, the Foundational Sciences Component Committee, and the Teacher Learner Advocacy Committee. He has been a member, team leader and committee chairman for numerous other IUSM curriculum committees including all those involved with the creation of the new medical school curriculum for the IUSM. He was the co-chairmanship of the Cardiovascular and Hematology UDOS course development team.

     Dr. Bell is a member of the American Physiological Society and the American Medical Writers Association. He has been married for 46 years to his wife Pamela who is a chemist, medical technologist, and high school AP chemistry educator. They have two children: Andrew who is a tax, estate and transactional attorney in Chicago and Elizabeth who is a board certified MD in both pediatrics and pediatric emergency medicine serving as a full time attending physician at the Detroit Medical Center.

Key Publications

Medical Physiology: Principles for Clinical Practice, 5th edition. RA Rhoades and DR Bell, editors, Wolters Kluwer/Lippincott, Williams and Wilkins, Baltimore, 3rd edtion 2009, 4th edition 2013, 5th edition 2018, 6th edtion 2021.

Core Concepts in Physiology. Bell DR. Lippincott-Raven, Philadelphia, New York, 1998

DR Bell. Vasoactive and Vasoprotective Anti-Oxidant Properties of Anthocyanin Enriched Berry Extracts, in ACS Symposium Series. Flavor Chemistry and Health Benefits of Small Fruits, A. Rimando and M. Qian, eds. American Chemical Society, 2009

 Nalliah, RE, JS Phillips, AJ Gaier, FL Jones, KE Gochenaur, DR Bell (corresponding author). Experimental in vitro arterial reactivity and tissue culture solutions alter the time dependent stability of anthocyanins from elderberry, chokeberry and bilberry extracts. Int J Food Sci Nutr  60: 209-219, 2009.

 Bell DR, K Gochenaur. Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts. J Appl Physiol 100: 1164-1170, 2006

Bell DR , Gochenaur KE, Hecht J. O2--mediated impairment of coronary arterial relaxation is prevented by overnight treatment with 1 nM  -estradiol J Appl Physiol 93: 1952-1958, 2002.

Bell DR, Rensberger HJ, Koritinik DR, Koshy A. Endothelium-dependent, NO-mediated vasorelaxation of porcine coronary arteries is potentiated directly by pretreatment with estrogen. Am J of Physiol 268(Heart Circ Physiol 37):H377-H383, 1995.

Bell DR, Bohr DF. Endothelium in functional aortic changes of coarctation hypertension. Am J Physiol 260(Heart Circ Physiol 29): H1187-H1193, 1991.

Bell DR, Sabbah HN, Stein PD. Profiles of velocity in the coronary arteries of dogs indicate lower shear rate along the inner arterial curvature. Arteriosclerosis 9:167-175, 1989.

 Bell DR, Overbeck HW: Intestinal hemodynamics in dogs with chronic one-kidney, one-wrapped hypertension. Am J Physiol 249:H300-H308, 1985.

Bell DR, Overbeck HW: Increased resistance and impaired maximal vasodilation in normotensive vascular beds of rats with coarctation hypertension. Hypertension 1:78-83, 1979.

 

Titles & Appointments

  • Associate Professor Emeritus of Anatomy, Cell Biology & Physiology
  • Education
    1983 PhD University of Alabama at Birmingham
    1977 MS Michigan State University
    1974 BS Michigan State University
  • Research

    Cardiovascular pathophysiology. Vascular abnormalities associate with hypertension. Modulation of vascular and endothelial function in coronary arteries by sex steroids and plant polyphenolics.

  • Professional Organizations
    American Medical Writers Association
    American Physiology Society
  • Awards
    Org:
    Desc: Trustee Teaching Award
    Scope: University
    Date: 2016-05-01

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