Andrew T. Templin, PhD
Assistant Professor of Medicine
- Phone
- (317) 983-3350
- Address
-
1210 Waterway Blvd
Indianapolis, IN 46202 - PubMed:
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Bio
Andrew Templin joined the faculty of the Division of Endocrinology in June 2020 and holds positions at the Indiana Biosciences Research Institute and the Roudebush VA Medical Center.
Prior to joining IU, Andrew served as an Acting Instructor of Medicine at the University of Washington in Seattle. During his time there, he studied the role of islet amyloidosis in islet inflammation and beta cell loss in collaboration with Dr. Steven Kahn. Dr. Templin’s work was funded by a Ruth L. Kirschstein National Research Service Award from the National Institutes of Health, and later by a Career Development Award from Veterans Affairs.
Andrew obtained his Ph.D. in Cellular and Integrative Physiology from IU under the mentorship of Dr. Raghu Mirmira, graduating in 2014. Prior to his doctoral work, he conducted medical research at Northwestern University’s Feinberg School of Medicine. Andrew received his Bachelor of Science degree from Indiana University in 2006, during which time he was a member of the Hutton Honors College.
Andrew’s work has been published in Diabetes, Diabetologia, Diabetes Care, the Journal of Biological Chemistry, and Proceedings of the National Academy of Sciences, among others.
Andrew is a native Hoosier who enjoys travel, soccer, the Chicago Cubs, and Golden Retrievers.
| Year | Degree | Institution |
|---|---|---|
| 2014 | Fellowship | University of Washington |
| 2014 | PhD | Indiana University |
| 2006 | BS | Indiana University |
Dr. Templin’s research focuses on understanding the relationship between islet immune responses and beta cell dysfunction and death in the setting of both major forms of diabetes. Emphasis is placed on the concept that beta cell intrinsic properties are drivers of islet inflammation and immune responses, and together these promote a system of beta cell dysfunction and loss leading to diabetes.
The Templin Lab investigates underappreciated mechanisms of inflammatory, lytic beta cell death and whether such forms of death can drive islet inflammation and further promote beta cell loss in diabetes. The Templin Lab also interrogates molecular mechanisms that underly amyloid-induced islet inflammation and beta cell loss in type 2 diabetes. These lines of research utilize in vitro models of beta cell death and in vivo models of islet amyloid formation, islet inflammation and beta cell loss to examine whether beta cells themselves promote islet inflammation in diabetes. Through this work, the Templin Lab aims to advance our understanding of beta cell loss in diabetes and improve the health of individuals afflicted with diabetes.
Templin AT; Schmidt C; Hogan MF; Esser N; Kitsis RN; Hull RL; Zraika S; Kahn SE; The Journal of endocrinology 2021 Sep 20
Mukherjee N; Lin L; Contreras CJ; Templin AT; Metabolites 2021 Nov 22
Templin AT; Mellati M; Meier DT; Esser N; Hogan MF; Castillo JJ; Akter R; Raleigh DP; Zraika S; Hull RL; Kahn SE; Diabetologia 2020 Jul 29
Kahn SE; Templin AT; Hull RL; Verchere CB; Diabetes care 2019 Feb
Templin AT; Mellati M; Soininen R; Hogan MF; Esser N; Castillo JJ; Zraika S; Kahn SE; Hull RL; Protein engineering, design & selection : PEDS 2019 Dec 13
Hogan MF; Ziemann M; K N H; Rodriguez H; Kaspi A; Esser N; Templin AT; El-Osta A; Kahn SE; Protein engineering, design & selection : PEDS 2019 Dec 13
Templin AT; Meier DT; Willard JR; Wolden-Hanson T; Conway K; Lin YG; Gillespie PJ; Bokvist KB; Attardo G; Kahn SE; Scheuner D; Hull RL; Diabetologia 2018 Jul 25
Templin AT; Samarasekera T; Meier DT; Hogan MF; Mellati M; Crow MT; Kitsis RN; Zraika S; Hull RL; Kahn SE; Diabetes 2017 Jul 20
Meier DT; Entrup L; Templin AT; Hogan MF; Mellati M; Zraika S; Hull RL; Kahn SE; Diabetologia 2016 Sep 1
Hogan MF; Meier DT; Zraika S; Templin AT; Mellati M; Hull RL; Leissring MA; Kahn SE; Endocrinology 2016 Jul 12
Meier DT; Tu LH; Zraika S; Hogan MF; Templin AT; Hull RL; Raleigh DP; Kahn SE; The Journal of biological chemistry 2015 Oct 19
Meier DT; Entrup L; Templin AT; Hogan MF; Samarasekera T; Zraika S; Boyko EJ; Kahn SE; The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2015 Aug
Templin AT; Maier B; Tersey SA; Hatanaka M; Mirmira RG; Molecular endocrinology (Baltimore, Md.) 2014 Sep 24
Liew CW; Assmann A; Templin AT; Raum JC; Lipson KL; Rajan S; Qiang G; Hu J; Kawamori D; Lindberg I; Philipson LH; Sonenberg N; Goldfine AB; Stoffers DA; Mirmira RG; Urano F; Kulkarni RN; Proceedings of the National Academy of Sciences of the United States of America 2014 May 19
Hatanaka M; Maier B; Sims EK; Templin AT; Kulkarni RN; Evans-Molina C; Mirmira RG; Diabetes 2014 May 16
Nishiki Y; Adewola A; Hatanaka M; Templin AT; Maier B; Mirmira RG; Molecular endocrinology (Baltimore, Md.) 2012 Dec 18
Tersey SA; Nishiki Y; Templin AT; Cabrera SM; Stull ND; Colvin SC; Evans-Molina C; Rickus JL; Maier B; Mirmira RG; Diabetes 2012 Apr
Templin AT; Maier B; Nishiki Y; Tersey SA; Mirmira RG; Cell cycle (Georgetown, Tex.) 2011 Apr 1