Alyssa D. Fajardo

Alyssa D. Fajardo, MD

Assistant Professor of Clinical Surgery


Dr. Fajardo obtained her medical degree from Indiana University School of Medicine, where she graduated as a member of the Alpha Omega Alpha honor society.   She also completed her general surgery training at IUSOM.  During this training, Dr. Fajardo spent two years as a research fellow at Washington University in St. Louis in the department of colorectal surgery.   She then returned to Washington University in St. Louis to complete a clinical fellowship in colorectal surgery and then joined IUSOM to join the Department of Surgery in the division of colon and rectal surgery.   She is a member and fellow of American College of Surgeons as well as the American Society of Colon and Rectal Surgery.  



Key Publications

 Escobar MA, Grosfeld JL, Burdick J, Powell R, Wait A, Jay C, West KW. Surgical Considerations in Cystic Fibrosis:  A 32 Year Evaluation of Outcomes.  Surgery.  2005. 138( 4)


Fajardo, AD. Robb, BW.  Chemoprevention for colorectal neoplasia.  Clinics in Colon & Rectal Surgery, 2008. 21(4): 404-412.


Fajardo AD*, Dharmarajan S*, George V, Hunt SR, Birnbaum EH, Fleshman JW, Mutch, MG.  Laparoscopic vs. Open 2 Stage Ileal Pouch:  Laparoscopic Approach Allows for Faster Restoration of Gastrointestinal Continuity.  J Am Coll Surg. 2010 Sep;211(3):377-83.


Fajardo AD, Chun J, Stewart D, Fleshman  JW. Evaluation of 1.5:1 Meshed AlloDerm Bolsters for Stapled Rectal Anastomoses in a Porcine Model.  Surg Innov. 2011 Mar;18(1):21-8.


Fajardo AD, Hunt SR, Fleshman JW, Mutch MG.  “Transanal Single Port Low Anterior Resection in a Cadaver Model.”  Surg Endosc. 2010 Jul;24(7):1765


Pardo I, Rager EL, Bowling MB, Fajardo AD, Clare S, Goulet Jr R. Central venous port placement: A comparison of axillary vs. anterior chest wall placement.  Ann Surg Oncol. 2011 Feb;18(2):468-71.


Waters JA, Guzman MJ,  Fajardo AD, Selzer DJ , Wiebke EA, Robb BW, George VV.  Single Port Laparoscopic Right Hemicolectomy: A Safe Alternative to Conventional Laparoscopy.  Dis Colon Rectum. 2010 Nov;53(11):1467-72.


Fajardo AD, Amador-Ortiz C, Chun J, Stewart D, Fleshman JW.  Evaluation of Bioabsorbable Seamguard® for Staple Line Reinforcement in Stapled Rectal Anastomoses. Surg Innov. 2012 Sep;19(3):288-94.


Dharmarajan S, Shuai D, Fajardo AD, Birnbaum EH, Hunt SR, Mutch MG, Fleshman JW, Lin AY. Clinically enlarged lateral pelvic lymph nodes do not influence prognosis after neoadjuvant therapy and TME in stage III rectal cancer.  .J Gastrointest Surg. 2011 Aug;15(8):1368-74.


Fajardo AD, Tan B, Fleshman JW. Delayed repeated intraperitoneal chemotherapy after cytoreductive surgery for colorectal and appendiceal carcinomatosis.  Dis Colon Rectum. 2012 Oct;55(10):1044-52.


George, VV, Fajardo, AD. (2014)  Long Axis rotational volvulus in an ileal J-Pouch anal anastomosis: A preventable rare complication. Case Reports in Clinical Medicine.  Vol.3, No.1, 28-31 DOI: 10.4236/crcm.2014.31007


George, V.  Velazco, L. , Munshi, I.  Robb, B. , Holcomb, B. , Ziegler, M. and Fajardo, AD. (2014) Cecum Schwannoma: Uncommon Colonic Mass and New Surgical Approach Using Single Site Laparoscopy. Case Reports in Clinical Medicine, 3, 181-185. doi: 10.4236/crcm.2014.33043.


Wennergren, J. , Munshi, I.  Fajardo, AD. and George, V. (2014) Implementation of Clinical Video Telemedicine (CVT) within a VA Medical Center Is Cost Effective and Well Received by Veterans. International Journal of Clinical Medicine, 5, 711-716. doi: 10.4236/ijcm.2014.512097.


Waters, J, Fajardo, AD, Holcomb, B, George, V, Robb, B, & Ziegler, M. (2015). Langerhans cell histiocytosis with anorectal involvement: a rare manifestation of adult disease. International journal of colorectal disease,30(5), 707-708.


Fajardo A. Complexities in Colorectal Surgery: Decision-Making and Management. Annals of Surgery. 2015 May 28.


Danforth, RM. Monn, MF., Spera, LJ, Fajardo, A, and George, VV, 2015. Safety and Short-term Outcomes of a Single-Port Laparoscopic Approach to Colorectal Surgery. JAMA surgery, 150(12), pp.1195-1197.


Dolejs, S. C., Gayed, B., & Fajardo, A. (2016). Prevention of Colorectal Neoplasia.  Clinics in Colon and Rectal Surgery, 29(04), 353-362.


Dolejs, S. C., Guzman, M. J., Fajardo, A. D., Robb, B. W., Holcomb, B. K., Zarzaur, B. L., & Waters, J. A. (2017). Bowel Preparation Is Associated with Reduced Morbidity in Elderly Patients Undergoing Elective Colectomy. Journal of gastrointestinal surgery: official journal of the Society for Surgery of the Alimentary Tract21(2), 372-379.






Book Chapters and Reviews



Clinical Scenarios in Surgical Oncology.  Editor Vijay P. Khatri.  Chapter 22: Duodenal Carcinoma/Adenoma.  Keith Lillemoe, MD, Wait, Alyssa D.  Publication date 01/2005.


Clinical Scenarios in Surgical Oncology.  Editor Vijay P. Khatri.  Chapter 46: Periampullary Carcinoma, Carcinomas of the Head of the Pancreas.  Keith Lillemoe, MD, Wait, Alyssa D. Publication date 01/2005


O’Neil, B. H., Fajardo, A. D., Wang, A., & Shahda, S. (2016). Local and Locally Advanced Rectal Cancer. Multidisciplinary Management of Gastrointestinal Cancers, 339.


(317) 948-7778 

General Surgery
Indianapolis, IN