Big Data, Informatics and Omics Core

The Big Data, Informatics and Omics Core contains the Computable Phenotype Research Core and the Clinical Trial Design and Omic Service Core. This group connects investigators and facilitates multidisciplinary research that leverages the use of novel technologies and resources to improve musculoskeletal health.

This core will support study design, statistical efforts, and informatics analysis of all Indiana Center for Musculoskeletal Health clinical research.

The Big Data, Informatics and Omics Core will also provide consultation with investigators seeking advanced data science and informatics methodology to develop appropriate hypotheses, design studies and identify collaborators, leveraging the extensive data science, informatics, genomics, biostatistics and machine learning expertise on campus.

Training

Expand the abilities of researchers by training cross-disciplinary collaborative teams in the use and application of novel tools, methodologies, designs and statistical analyses.

Research

Enhance clinical research by leveraging large databases to define and validate relevant computer musculoskeletal phenotypes (computer algorithms to identify particular characteristics of outcomes).

Clinical Trials

This core interacts with investigators and members of thematic research teams to accelerate the human to bench and back cycle of discovery through the characterization of genotypes and molecular musculoskeletal phenotypes.

Related Publications

Luo X, Ding H, Broyles A, Warden SJ, Moorthi RN, Imel EA. Using machine learning to detect sarcopenia from electronic health records. DIGITAL HEALTH. 2023;9.