Herman B Wells Center for Pediatric Research

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Pulmonary Inflammation, Asthma and Allergic Diseases

Allergic diseases are increasing in frequency and represent a significant health concern in the United States–affecting approximately 1 in 5 Americans today. Atopic dermatitis, often referred to as allergic skin inflammation or eczema, is frequently the first step on the atopic march, a series of allergic responses localized to the nares (allergic rhinitis), esophagus (eosinophilic esophagitis), intestinal tract (food allergy) and the airways (allergic asthma). The severity of these diseases can vary from mild annoyances to life-threatening illness.

The Wells Center investigators studying pulmonary inflammation, asthma and allergic diseases understand the initiation, pathogenesis and progression of these allergic diseases in the hopes of identifying better ways to treat or prevent allergic symptoms. Studies explore many areas, including the regulation of genes important for the development of T cells involved in allergic inflammation, lung development/ function and how changes contribute to lung reactivity. Research involves animal models of developmental cardiopulmonary defects, allergic inflammation and viral infection as well as patient studies of infants and children with atopic dermatitis and developing airway disease.

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Areas of expertise

Areas of expertise

Researchers in the Pulmonary Inflammation, Asthma and Allergy group are experts in lung development and function and allergic disease.
Active research

Active research

Learn more about the research laboratories of each principal investigator within the Pulmonary Inflammation, Asthma and Allergy group.
FAQ

FAQ

Find answers to common questions about allergic diseases and the atopic march.
7
Principal investigators
3
Million annually in research funds
12
Trainees

Faculty Research Team

Simon J. Conway, PhD

Simon J. Conway, PhD

Professor of Pediatrics
Mark H. Kaplan, PhD

Mark H. Kaplan, PhD

Billie Lou Wood Professor of Pediatrics
Joan M. Cook-Mills

Joan M. Cook-Mills

Professor of Pediatrics
Robert S. Tepper, MD,  PhD

Robert S. Tepper, MD, PhD

Mary Agnes Kennedy and Katheryn Kennedy Weinberger Professor of Pediatrics
Matthew J. Turner, MD PhD

Matthew J. Turner, MD PhD

Assistant Professor of Dermatology
Kai Yang, PhD

Kai Yang, PhD

Assistant Professor of Pediatrics
Baohua Zhou, PhD

Baohua Zhou, PhD

Associate Professor of Pediatrics