Herman B Wells Center for Pediatric Research

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Hematologic Malignancies and Stem Cell Biology Research

Hematologic malignancies and stem cell biology research is focused on comparing molecular and cellular regulation of stem and progenitor cell populations in hematopoietic, endothelial and mesenchymal lineages using studies performed in human, murine and other species. Stem cell biology in the context of development, homeostasis and leukemic transformation is examined to understand the genetic basis for normal lineage specification and maintenance.