Centers and Institutes

Indiana Center for Regenerative Medicine and Engineering

Super-resolution image of the basal expression of myosin light chain and phosphorylated myosin light chain in mice embryonic fibroblast. Scale 2 μm

Super-resolution image of the basal expression of myosin light chain and phosphorylated myosin light chain in mice embryonic fibroblast. Scale 2 μm

The Indiana Center for Regenerative Medicine and Engineering is a multidisciplinary research center focused on the development of novel technologies that regenerate cells and tissues affected by age, disease, damage or congenital effects, ultimately leading to wound care and healing for patients in Indiana and beyond. Located on the Indiana University School of Medicine – Indianapolis campus, the center is comprised of more than 30 scientists and staff working to reduce the number of amputations in the state of Indiana and deliver critically acclaimed science.

Center Leadership

Chandan Sen, PhD

Director, Center for Regenerative Medicine and Engineering

Chandan Sen, PhD, serves as the Vice Chair of Research at Indiana University School of Medicine Department of Surgery. He also serves as the Director of the Indiana Center for Regenerative Medicine and Engineering. Dr. Sen’s team is made up of more than 30 scientists and staff who study how to tap into the power of regenerative medicine and engineering to heal burns, develop new therapies for diabetic complications, treat injured soldiers, and even regrow damaged and diseased tissue.

Mervin C. Yoder, MA, MD

Director Emeritus, Indiana Center for Regenerative Medicine and Engineering

Mervin C. Yoder, MA, MD, became an Assistant Professor of Pediatrics at the Indiana University School of Medicine in 1985, and was awarded tenure in 1991, and promoted to Professor of Pediatrics and of Biochemistry and Molecular Biology in 2000. In 2004, Dr. Yoder was named the Richard and Pauline Klingler Professor of Pediatrics. In March 2008, he was promoted to Director of the Herman B. Wells Center for Pediatric Research and Associate Chair for Basic Research in the Department of Pediatrics. In 2011 he was chosen to serve as Assistant Dean for Entrepreneurial Research for the IU School of Medicine and Associate Director for Entrepreneurship for the Indiana Clinical and Translational Sciences Institute. He was promoted to Distinguished Professor in 2013.

Interdisciplinary Collaboration

Regenerative medicine solutions require expertise across disciplines in medicine and engineering to develop transformative solutions in science and health care. With support from the state of Indiana, philanthropic donors, foundations and the federal government, the center partners with private industry to develop new treatments for disease.

The center’s team of investigators are located throughout the state of Indiana, converging toward excellence in regenerative medicine and engineering, in partnership with industry and government agencies. Together, this team is working to address four core pillars: Cell-Based Therapies; Tissue Engineering; Wound, Burn, and Inflammation; and Military Health.

The power of healing through innovative technology

Emerging Training Program

The Center for Regenerative Medicine and Engineering at IU School of Medicine is in the process of developing the nation’s first PhD program in regenerative medicine and engineering with opportunities for industry internship.

Tissue Nanotransfection

Tissue Nanotransfection

Investigators at the Center have developed a non-invasive, nanochip device that uses tissue nanotransfection technology to reprogram one type of tissue into another with a simple touch and electric spark that is harmless to the body.
What is regenerative medicine?

What is regenerative medicine?

Regenerative medicine is the process of creating living, functional tissues to repair or replace tissue or organ function loss due to age, disease, damage or congenital effects.