Mechanobiology and 3D Bioprinting Core

Led by Alexander Robling, PhD, and Joseph Wallace, the Mechanobiology and 3D Bioprinting Core, now under development for early 2019 opening, will offer services related to in vivo skeletal loading, in vivo muscle loading, in vivo disuse experiments (for both bone and muscle), and scaffold-free bioprinting via a novel instrument that provides unprecedented versatility.

The goals of the core center on both mechanotransduction and 3D bioprinting, providing in vivo bone and muscle mechanotransduction services, including anabolic (ulnar loading, tibia loading, muscle electrostimulation), and catabolic (tail suspension, Botox paralysis) techniques as well as in vitro bone and muscle cell mechanotransduction services, including parallel plate fluid flow and substrate strain techniques.

The Mechanobiology and 3D Bioprinting Core will also Provide 3D bioprinting services to ICMH investigators for their in vitro or in vivo models and applications and, by combining mechanobiology with 3D bioprinting, innovate and advance the field in technical aspects while providing quality control and training/education for more standard techniques.