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The Indiana University Melvin and Bren Simon Cancer Center is one of the leading academic cancer research centers in the United States. It is located on the IU School of Medicine–Indianapolis campus. More than 200 scientists affiliated with the center conduct research in four different programs. The goals of these programs range from understanding the molecular changes that cause cancer to developing targeted therapies to prevent and treat cancer.

Since its founding, researchers at the center have made protocol-defining discoveries that have changed the way doctors treat breast cancer; gastrointestinal cancer, including pancreatic and colon cancers; genitourinary cancer, such as germ cell tumors, bladder and prostate cancer; hematologic disorders, including multiple myeloma and leukemia; bone marrow and stem cell transplantation programs; thoracic cancer; thymoma; and thymic carcinoma.

Advanced Clinical Research

The IU Simon Cancer Center has earned international recognition for novel and clinical cancer research. Each year, IU School of Medicine physician-researchers at the IU Simon Cancer Center lead more than 600 active clinical trials for pediatric and adult cancers. Those trials may lead to tomorrow’s therapies.

Active Research Programs

Tumor Microenvironment and Metastasis

Tumor Microenvironment and Metastasis

The Tumor Microenvironment and Metastasis program’s discoveries lead to clinical trials in collaboration with other Simon Cancer Center research programs.
Cancer Prevention

Cancer Prevention

The Cancer Prevention and Control (CPC) research program focuses on cancer risk reduction and early detection as well as survivorship and symptom science.
Therapeutics

Therapeutics

Research focused on experimental and developmental therapeutics seeks to develop mechanism-based therapy for human cancer.
Other Program

Other Program

Other Program is focused on experimental and developmental therapeutics seeks to develop mechanism-based therapy for human cancer.

Physician Scientists

Kathy D. Miller, MD

Kathy D. Miller, MD

Ballv Lantero Professor of Oncology
Rich C. Zellars, MD

Rich C. Zellars, MD

Chair, Department of Radiation Oncology

National Recognition

The IU Simon Cancer Center is one of only 70 National Cancer Institute (NCI)-designated cancer centers in the nation and the only one in Indiana that provides patient care. The NCI designation recognizes that the center’s collaborative research programs meet the NCI’s rigorous criteria for world-class, state-of-the-art programs in multidisciplinary cancer research that reaches all 92 counties in Indiana. It also means that the scientific discoveries made by researchers at the IU Simon Cancer Center benefit patients close to home.

Patient-Focused Partnership

Through a close and long-standing partnership with Indiana University Health, cancer patients benefit from the scientific discoveries made at the IU Simon Cancer Center. IU Health provides multidisciplinary clinical care for adults with cancer at IU Health Simon Cancer Center and for children at Riley Hospital at IU Health.

Education

Education

Faculty educators train nearly 2000 students, residents and fellows each year.
Research

Research

Physician and scientific investigators collaborate to target clinical problems to be addressed and speed the translation of laboratory research into new treatments.
Giving

Giving

Donor support advances research that has regional, national and global impact.