The Center for Medical Genomics offers DNA/RNA quantification, DNA quality control and fragment-size analysis, RNA quality (measure of fragmentation/degradation), and miRNA quality. DNA/RNA Analysis services include quality/quantity assessment as well as shearing and sample extraction. Instruments include NanoDrop, Agilent 2100 Bioanalyzer, Qubit Fluorometer, and Covaris S2 Focused-ultrasonicator.
Single cell analysis includes single cell RNA-seq, single nucleus RNA-seq, single cell ATAC-seq, single cell copy number variation (CNV) and single cell immune profiling. The center is equipped with three 10x Genomics Chromium Systems. Investigators are responsible for preparing high-quality single-cell suspension from biological specimens. FAQs about single cell studies give additional details about this service.
The Center for Medical Genomics offers whole genome sequencing, whole exome sequencing, gene panel target sequencing, 10x LinkedRead sequencing and ChIP-seq.
RNA sequencing services include whole transcriptome sequencing, mRNA sequencing, and miRNA sequencing. FAQs about RNA-sequencing give additional details about this service.
Metagenomics services include 16S sequencing and shotgun sequencing.
The Center for Medical Genomics offers high-throughput targeted genotyping using single-nucleotide polymorphism (SNP), allele-specific expression and validation of methylation sites. The center uses the Sequenom MassArray® system for targeted genotyping, generally in groups of up to 25 or 30 SNPs per assay and can be used to genotype SNPs in any organism.