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Research Cores

Research Service Cores

Service core laboratories provide medical researchers with specialized scientific services to support their studies. With these resources, scientists at IU School of Medicine and partner organizations can access state-of-the-art instrumentation and equipment, technical expertise, and training that advances their work.

Biological Microscopy

The Indiana Center for Biological Microscopy is a light microscopy core facility that provides state-of-the-art imaging capabilities to Indiana University scientists. Researchers are trained to operate facility equipment, which they may use independently at a reasonable hourly rate.

Chemical Genomics

The Chemical Genomics Core Facility is conveniently located within Indiana University School of Medicine, Indianapolis, and provides cost-effective access to high-throughput screening of structurally diverse, drug-like small molecules in both biochemical and cell-based assays; sophisticated small molecule informatics, design and synthesis; cell imaging-based high content analysis; and small and large molecule analysis to both academic and industrial investigators. The Chemical Genomics Core Facility enables discovery of small molecule tools for basic research, therapeutic development and diagnostic applications.

Computational Biology and Bioinformatics

The Computational Biology and Bioinformatics Service Core (Indianapolis), a service unit of the Center for Computational Biology and Bioinformatics, provides biomedical data management, informatics and analytical consulting, graphic and website design, and software and website hosting.


The Center for Diabetes and Metabolic Diseases at IU School of Medicine offers five research cores to provide resources for collaborative partnerships and state-of-the-art methodologies that support innovative translational research.

Electron Microscopy

The IU School of Medicine Electron Microscopy Center (Indianapolis) is a full-service research laboratory that provides both transmission and scanning electron microscopy. The center can provide the technical services to help design and then implement experiments needing either type of microscopy.


The Histology Core (Indianapolis) provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared by the facility.

Imaging and Flow Cytometry

The IU School of Medicine Imaging and Flow Cytometry Core facility (South Bend), houses multiple types of laser-scanning equipment that are available to all faculty and staff of IU School of Medicine and the University of Notre Dame.


The Immunohistochemistry Core (Indianapolis) offers histologic and immunohistochemical labeling of cells or tissue sections to support biomedical researchers This facility also collaborates with surgical pathologists.

Laboratory Animal Resource Center

The veterinary staff and other highly experienced laboratory animal professionals of the IU School of Medicine Laboratory Animal Resource Center provides training, supplies and specialized service support for medical research. Services center on basic husbandry for a wide variety of laboratory animal species.

Medical Genomics

The Center for Medical Genomics (Indianapolis) at Indiana University School of Medicine is equipped with a variety of advanced genomics technologies, including next-generation sequencing and microarray and single-nucleotide polymorphism (SNP) genotyping instrumentation.

Micro Computed Tomography

The Micro Computed Tomography Core (Indianapolis) houses two Skyscan systems with the versatility to scan skeletal and non-soft biological tissues at high resolution. Scan reconstruction and analysis software can be used on the scanning systems, or they can be installed on individual laboratory workstations. Self-service or full-service scanning is available.

Research Imaging

The Office for Research Imaging (Indianapolis) plans and implements complex imaging protocols within the vast resources offered through IU Health, IU School of Medicine centers and the school’s other clinical partners.