Tune Lab

The research lab of Johnathan D. Tune, PhD focuses on the regulation of coronary blood flow, contractile function and metabolism in health and disease.

Active Research

Research in the Tune Lab focuses on the regulation of coronary blood flow, contractile function and metabolism in health and disease. The laboratory has been continuously funded for more than 15 years by the National Institutes of Health, the American Heart Association and the American Diabetes Association as well as pharmaceutical companies to elucidate mechanisms of impaired coronary and cardiac function in the setting of obesity and diabetes. The lab’s studies routinely include a series of experimental approaches utilizing both in vivo (chronically instrumented conscious and/or acute open-chest swine) and in vitro (isolated artery rings, pressurized arterioles, Western blot, RT-PCR, immunohistochemistry, confocal microscopy) methodologies to examine hypotheses in a highly integrative manner. These studies have led to more than 95 peer-reviewed publications and the successful training of numerous post-doctoral fellows, PhD and MS students.

Recent Publications

A full list of Dr. Tune’s publication history is available on PubMed. Access to full length versions of publication can be found on Tune Research Gate.

Faculty Research Team

Johnathan D. Tune, PhD

Johnathan D. Tune, PhD

Professor of Cellular & Integrative Physiology
Adam G. Goodwill, PhD

Adam G. Goodwill, PhD

Assistant Research Professor of Cellular & Integrative Physiology

Additional Research Team Members

Other research team members in the Tune Lab include Joshua Sturek (Research Assistant).