7-14-BS-053 (Elmendorf, PI), 01/01/15-12/31/17
“Mechanisms of Membrane Cholesterol Accumulation and Insulin Resistance”
The goal of this grant is to determine mechanisms of membrane cholesterol accumulation and glucose transporter 4 dysregulation in skeletal muscle.
R01HL117620 (Tune, PI) , 02/01/13-01/31/18
“Cardiovascular Effects of GLP-1 in Obesity/Metabolic Syndrome”
The main goal of our investigations on this grant is to determine the effects of GLP-1 on cardiac glucose and lipid transporters in obesity/metabolic syndrome.
P30DK097512 (Mirmira, PI), 04/01/15-03/31/20
“Indiana Diabetes Research Center”
This center grant establishes Research Cores, Pilot & Feasibility funding, and Enrichment activities in support of diabetes and metabolic research at Indiana University School of Medicine.
Role: Director of Pilot & Feasibility Program
Indiana Clinical & Translational Sciences Institute Predoctoral Award (Gohn, PI), 07/01/15-06/30/17
“MEOX2 Regulation of Fetal Endothelial Colony Forming Cell Senescence”
The main goal of this predoctoral fellowship is to establish Mesenchymal Homeobox 2 (MEOX2) as a biomarker to identify children most at risk for developing cardiovascular disease.
Han X, Quinney SK, Wang Z, Zhang P, Duke J, Desta Z, Elmendorf JS, Flockhart DA and Li L. Identification and Mechanistic Investigation of Drug-Drug Interactions Associated With Myopathy: A Translational Approach. Clin Pharmacol Ther. 2015;98:321-7
Tunduguru R, Chiu TT, Ramalingam L, Elmendorf JS, Klip A and Thurmond DC. Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells. Biochem Pharmacol. 2014;92:380-8.
Faculty Research Team
Additional Research Team Members
Other research team members in the Elmendorf Lab include Brian A. Grice, Predoctoral MD/PhD Fellow, and Lixuan Tackett, MS, Technician.