Herman B Wells Center for Pediatric Research

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Active Research

Investigators in the Pulmonary Inflammation, Asthma and Allergic Diseases research group examine the genetic and environmental factors that lead to allergic and autoimmune diseases such as atopic dermatitis, allergic asthma and food allergy.

The overarching goal of their research is to advance understanding in disease initiation, pathogenesis and progression in order to better assess risk for disease, improve treatments and prevent severe reactions.

Learn more about the research laboratories of the group’s principal investigators and how each is working to advance scientific understanding related to allergic and autoimmune disease.

The Kaplan Laboratory focuses on transcription factors involved in the development of T helper cell subsets and how those cells contribute to inflammation in allergic and autoimmune diseases. Overall, the goal of this work is to identify biomarkers for the development of personalized medicine and disease intervention.

The Cook-Mills Laboratory explores the genetic and environmental factors that contribute to the development of allergic disease with hopes of developing regulatory therapies to prevent severe allergic reaction.

The Conway Laboratory seeks to identify the mechanisms and cell lineages responsible for cardiopulmonary disease development and transgenically and/or pharmacologically current the various structural and functional defects.

The Tepper Laboratory focuses on the lung structure and function related to airway hyper-reactivity as well as lung growth and maturation in vivo and in vitro.

The Turner Lab studies the interaction between skin injury, inflammation and wound healing.  The goal of the Turner Lab is to discover new molecular pathways that promote inflammatory skin diseases and impair wound healing in order to translate these discoveries into new and better treatments for patients.

The Yang Laboratory seeks to identify key molecular and metabolic components involved in the initiation and progression of allergic diseases with the long-term goal of developing novel treatment strategies for allergic disease.

The Zhou Laboratory focuses on the interaction of effector T helper cells and regulatory T cells in the pathogenesis of allergic and auto immune disease.