Musculoskeletal Health

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Clinical Research Cores

The Clinical Research Core serves as the cornerstone for human subjects research conducted in the Indiana Center for Musculoskeletal Health and receives funding through a P30 grant from NIH NIAMS. This team is working to better define musculoskeletal diseases that have common pathogenesis and clinical presentations.

Integrated Investigator Team

With the exemplary team of investigators, the core has integrated a network of electronic health records and molecular profiles to identify genetic factors, clinical and biochemical phenotypes, and to standardize physical function measurements and imaging modalities to define the diseases’ functional and morphologic phenotypes. Improving the definition and diagnosis of these musculoskeletal conditions could lead to personalized medicine advances, enabling health care providers to prescribe tailored treatment for each patient.

The Function, Imaging, and Tissue Resource Core offers standardized imaging outcomes for bone and muscle health assessments and a standardized data entry platform for physical function outcomes and training in the performance and interpretation of these outcomes. Specimens and tissues related to musculoskeletal health are available through the Indiana Biobank.

The Big Data and Omics Methods Core contains the Computable Phenotype Research Core and the Clinical Trial Design and Omics Service Cores. This group connects investigators and facilitates multi-disciplinary research that leverages the use of novel technologies and resources to improve musculoskeletal health.

The Administrative Core oversees communications, pilot funding, and training programs for the Center for Musculoskeletal Health at IU School of Medicine to facilitate cross-disciplinary clinical research.

Clinical Research Core Leadership

Sharon M. Moe, MD

Sharon M. Moe, MD

Stuart A. Kleit Professor of Nephrology
Michael J. Econs, MD

Michael J. Econs, MD

Glenn W. Irwin, Jr. Professor of Endocrinology and Metabolism
 Stuart J. Warden, PhD

Stuart J. Warden, PhD

Adjunct Associate Professor of Anatomy & Cell Biology
Connie Weaver, PhD

Connie Weaver, PhD

Distinguished Professor at Purdue University