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Indiana Center for Musculoskeletal Health Research Teams

Focused research teams are composed of basic, translational and clinical researchers, including medical and graduate students, post-doctoral fellows, and orthopaedic fellows. These cross-departmental research teams also include experts in genetics and precision medicine, trauma, rehab, regeneration, mechanobiology and bone/muscle crosstalk, musculoskeletal cancer, and pediatric musculoskeletal disease.

Cancer in Bone and Muscle

The rising burdens of musculoskeletal diseases include various types of cancer in bone. The Cancer in Bone and Muscle research team focuses on the interactions between bone and cancer, especially breast and prostate cancer as well as multiple myeloma. Additionally, these investigators are interested in understanding the interaction of bone cancers to muscle cachexia and vice-versa. Team Leaders: Theresa Guise, MD and David Roodman, MD, PhD.

Teresita M. Bellido, PHD

Professor of Anatomy, Cell Biology, & Physiology

John M. Chirgwin, PHD

Professor of Medicine

Jesus Delgado-Calle, PHD

Assistant Research Professor of Medicine

Melissa A. Kacena, PHD

Professor of Orthopaedic Surgery

Patrick J. Loehrer, MD

Distinguished Professor

Khalid S. Mohammad, PHD, MBBCH

Senior Research Professor of Medicine

Lilian I. Plotkin, PHD

Associate Professor of Anatomy, Cell Biology & Physiology

Uma Sankar, PHD

Associate Professor of Anatomy, Cell Biology & Physiology

Attaya Suvannasankha, MD

Associate Professor of Clinical Medicine

Trupti Trivedi, PHD

Postdoctoral Fellow in Medicine

William R. Thompson, PHD

Assistant Professor of Physical Therapy, School of Health & Human Sciences

Teresa A. Zimmers, PHD

H.H. Gregg Professor of Cancer Research

Lifestyle Modification: Physical Activity and Nutrition

The lifestyle modification team’s research focuses on the lifestyle, nutrition, and behavioral modifications that impact musculoskeletal health and physical function, specifically in regards to nutrition and mobility. The goals of this research is to better understand how musculoskeletal health and physical function affect the overall health of the population and how chronic diseases impact musculoskeletal health. Team Leaders: NiCole Keith, PhD, and Ranjani Moorthi PhD.

Keith G. Avin, PHD

Adjunct Assistant Research Professor of Medicine

Tarah J. Ballinger, MD

Assistant Professor of Clinical Medicine

Robyn K. Fuchs, PHD

Adjunct Associate Research Professor of Anatomy, Cell Biology & Physiology

Kathleen M. Hill Gallant, PHD

Adjunct Assistant Research Professor of Medicine

Babar A. Khan, MB,BS

Associate Professor of Medicine

Patricia J. Scott, PhD

Adjunct Professor of Surgery

Michael Sturek, PHD

Professor of Anatomy, Cell Biology & Physiology

Stuart J. Warden, PHD

Adjunct Professor of Anatomy, Cell Biology & Physiology

Connie M. Weaver, PHD

Adjunct Professor of Pharmacology & Toxicology

Teresa A. Zimmers, PHD

H.H. Gregg Professor of Cancer Research

Mechanobiology and Muscle/Bone Crosstalk

Focusing on osteoarthritis, effects of exercise on the musculoskeletal system and the new research area of non-mechanical, systematic interactions between muscle and bone, this research team currently includes over 30 musculoskeletal health investigators. To make the most of the collaboration opportunities in a research team this size, leaders David Burr and Teresa Zimmers have organized the team into sub-groups that target specific research goals for experimenting, development, and funding. Team Leaders: David Burr, PhD, and Teresa Zimmers, PhD.

Keith G. Avin, PHD

Adjunct Assistant Research Professor of Medicine

Teresita M. Bellido, PHD

Professor of Anatomy, Cell Biology, & Physiology

Angela Bruzzaniti, PHD

Associate Professor of Oral Biology, School of Dentistry

Neal X. Chen, MD, PHD

Associate Research Professor of Medicine

Tien-Min G. Chu, PHD

Associate Dean for Research, School of Dentistry

Robyn K. Fuchs, PHD

Adjunct Associate Research Professor of Anatomy, Cell Biology & Physiology

Theresa A. Guise, MD

Jerry W. and Peggy S. Throgmartin Professor of Oncology

Nilsson Holguin, PHD

Adjunct Assistant Professor of Anatomy, Cell Biology & Physiology

Jiliang Li, MD, PHD

Adjunct Associate Professor of Anatomy, Cell Biology & Physiology

Margaret A. McNulty, PHD

Assistant Professor of Anatomy, Cell Biology & Physiology

Khalid S. Mohammad, PHD, MBBCH

Senior Research Professor of Medicine

Fredrick M. Pavalko, PHD

Professor of Anatomy, Cell Biology & Physiology

Thomas M. O'Connell, PHD

Associate Professor of Otolaryngology-Head & Neck Surgery

Lilian I. Plotkin, PHD

Associate Professor of Anatomy, Cell Biology & Physiology

Alexander G. Robling, PHD

Professor of Anatomy, Cell Biology & Physiology

Uma Sankar, PHD

Associate Professor of Anatomy, Cell Biology & Physiology

Michael Sturek, PHD

Professor of Anatomy, Cell Biology & Physiology

William R. Thompson, PHD

Assistant Professor of Physical Therapy, School of Health & Human Sciences

Stephen B. Trippel, MD

Professor Emeritus of Orthopaedic Surgery

Joseph Wallace, PHD

Associate Professsor, School of Engineering & Technology

Stuart J. Warden, PHD

Adjunct Professor of Anatomy, Cell Biology & Physiology

Hiroki Yokota, PHD

Adjunct Professor of Anatomy, Cell Biology & Physiology

Pediatric Musculoskeletal Disease

The pediatric musculoskeletal disease team is investigating the causes of childhood musculoskeletal diseases, including those that affect bone and muscle such as diabetes, obesity, and the sarcomas with special interest on osteosarcoma. The goal is better understand the causes of pediatric musculoskeletal disease and how they relate to other childhood illnesses. Team Leaders: Linda DiMeglio, MD and Erik Imel, MD.

Imranul Alam, PHD

Assistant Research Professor of Medicine

Tyler W. Christman

Assistant Professor of Clinical Orthopaedic Surgery

Linda A. DiMeglio, MD

Professor of Pediatrics

Marcia V. Felker, MD

Assistant Professor of Clinical Neurology

Erik A. Imel, MD

Associate Professor of Medicine

Melissa A. Kacena, PHD

Professor of Orthopaedic Surgery

Precision Medicine

The precision medicine team is focused on genetic musculoskeletal diseases, such as X-linked hypophosphatemia, autosomal dominant hypophosphatemia, and genomic, metabolomics, protemic determinants of bone density, osteoporosis and sarcopenia in aging and chronic disease. These investigators focusing on the causes of these diseases, and working to develop treatments and cures. Team Leaders: Todd Skaar, PhD and Ken White, PhD.

Matthew R. Allen, PHD

Assistant Dean for Faculty Affairs and Professional Development

Teresita M. Bellido, PHD

Professor of Anatomy, Cell Biology, & Physiology

Angela Bruzzaniti, PHD

Associate Professor of Oral Biology, School of Dentistry

Neal X. Chen, MD, PHD

Associate Research Professor of Medicine

Michael J. Econs, MD

Distinguished Professor

Erik A. Imel, MD

Associate Professor of Medicine

Uma Sankar, PHD

Associate Professor of Anatomy, Cell Biology & Physiology

Trauma Regeneration and Rehabilitation

Team Leaders: Melissa Kacena, PhD, Brian Mullis, MD.

Focusing on developing patient-specific interventions, these investigators are working to treat patients sustaining musculoskeletal injury, specifically injuries that result in acute and chronic musculoskeletal disease. These treatment goals include acute interventions, regenerative interventions for both bone and muscle, and eventually identifying the optimal means of rehabilitation for the patient to resume a normal lifestyle.

Keith G. Avin, PHD

Adjunct Assistant Research Professor of Medicine

Mary Beth Brown, PHD

Adjunct Associate Professor of Medicine

Angela Bruzzaniti, PHD

Associate Professor of Oral Biology, School of Dentistry

Tien-Min G. Chu, PHD

Associate Dean for Research, School of Dentistry

Thomas J. Fischer, MD

Adjunct Clinical Associate Professor of Orthopaedic Surgery

Melissa A. Kacena, PHD

Professor of Orthopaedic Surgery

Nilsson Holguin, PHD

Adjunct Assistant Professor of Anatomy, Cell Biology & Physiology

Jiliang Li, MD, PHD

Adjunct Associate Professor of Anatomy, Cell Biology & Physiology

Farzad Loghmani, MD

Assistant Professor of Clinical Medicine

Todd O. McKinley, MD

Professor of Orthopaedic Surgery

Brian H. Mullis, MD

Professor of Orthopaedic Surgery

Uma Sankar, PHD

Associate Professor of Anatomy, Cell Biology & Physiology

Stephen B. Trippel, MD

Professor Emeritus of Orthopaedic Surgery

Stuart J. Warden, PHD

Adjunct Professor of Anatomy, Cell Biology & Physiology

Hiroki Yokota, PHD

Adjunct Professor of Anatomy, Cell Biology & Physiology

Teresa A. Zimmers, PHD

H.H. Gregg Professor of Cancer Research