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Mechanobiology and 3D Bioprinting Core

Led by William Thompson, PhD, the Mechanobiology Core, now under development for early 2019 opening, will offer services related to in vivo skeletal loading, in vivo muscle loading, and in vivo disuse experiments (for both bone and muscle).

The 3D bioprinting core, led by Lester Smith, PhD, provides scaffold-free bioprinting via a novel instrument that provides unprecedented versatility.

The goals of the cores focus on both mechanotransduction and 3D bioprinting, providing in vivo bone and muscle mechanotransduction services, including anabolic (ulnar loading, tibia loading, muscle electrostimulation), and catabolic (tail suspension, Botox paralysis) techniques as well as in vitro bone and muscle cell mechanotransduction services, including parallel plate fluid flow and substrate strain techniques.

The Mechanobiology and 3D Bioprinting Core also provides 3D bioprinting services to Indiana Center for Musculoskeletal Health investigators for their in vitro or in vivo models and applications and, by combining mechanobiology with 3D bioprinting, innovate and advance the field in technical aspects while providing quality control and training/education for more standard techniques.